aminopyrine: meaning, definition, pronunciation and examples

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UK/əˌmiːnəʊˈpaɪəriːn/US/əˌminoʊˈpaɪriːn/

Technical/Medical

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Quick answer

What does “aminopyrine” mean?

A synthetic, white crystalline powder historically used as an analgesic (pain reliever) and antipyretic (fever reducer).

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Pronunciation

Definition

Meaning and Definition

A synthetic, white crystalline powder historically used as an analgesic (pain reliever) and antipyretic (fever reducer).

A pyrazolone derivative drug, also known chemically as 4-dimethylamino-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one. Its medical use has been largely discontinued in many countries due to the risk of causing agranulocytosis, a severe blood disorder.

Dialectal Variation

British vs American Usage

Differences

No significant difference in meaning or usage. The spelling is identical. The drug is equally obsolete in both medical communities.

Connotations

Carries connotations of outdated pharmacology and significant medical risk.

Frequency

Extremely rare in both varieties, appearing only in specialised texts.

Grammar

How to Use “aminopyrine” in a Sentence

Aminopyrine was used [to treat headaches].The use of aminopyrine [has been discontinued].Aminopyrine causes/severe side effects.

Vocabulary

Collocations

strong
analgesic and antipyreticagranulocytosispyrazolone derivativehistorical use
medium
withdraw aminopyrineadministration of aminopyrinetoxicity of
weak
effects ofrelated to

Examples

Examples of “aminopyrine” in a Sentence

adjective

British English

  • The aminopyrine metabolite was detected.
  • An aminopyrine-related toxicity case.

American English

  • The aminopyrine metabolite was detected.
  • An aminopyrine-related toxicity case.

Usage

Meaning in Context

Business

Not used.

Academic

Used in historical reviews of pharmacology, toxicology case studies, and discussions of drug safety regulations.

Everyday

Never used in everyday conversation.

Technical

Used precisely in medical, pharmaceutical, and chemical texts to refer to the specific compound and its properties.

Vocabulary

Synonyms of “aminopyrine”

Neutral

Pyramidon (a former brand name)

Watch out

Common Mistakes When Using “aminopyrine”

  • Misspelling as 'aminopyrin' or 'aminopirin'.
  • Assuming it is a current or safe medication.

FAQ

Frequently Asked Questions

No, it has been discontinued in most of the world due to the risk of causing a dangerous drop in white blood cells (agranulocytosis).

It is a derivative of pyrazolone, which is a class of organic compounds.

It is a significant case study in pharmacology and drug safety, highlighting the importance of post-marketing surveillance and the evolution of medical regulations.

It was widely marketed under the brand name Pyramidon in many countries.

A synthetic, white crystalline powder historically used as an analgesic (pain reliever) and antipyretic (fever reducer).

Aminopyrine is usually technical/medical in register.

Aminopyrine: in British English it is pronounced /əˌmiːnəʊˈpaɪəriːn/, and in American English it is pronounced /əˌminoʊˈpaɪriːn/. Tap the audio buttons above to hear it.

Learning

Memory Aids

Mnemonic

Think: AMINO (relating to its chemical structure with an amino group) + PYRINE (sounds like 'pyre' for fever, hinting at its antipyretic use).

Conceptual Metaphor

A DANGEROUS RELIC: Conceptualised as a tool from a less cautious era of medicine, now shelved due to its inherent danger.

Practice

Quiz

Fill in the gap
Due to its association with , the drug aminopyrine was withdrawn from the market in many nations.
Multiple Choice

In what context is the word 'aminopyrine' most likely to be encountered today?