antihistamine: meaning, definition, pronunciation and examples

B2
UK/ˌæn.tiˈhɪs.tə.miːn/US/ˌæn.tiˈhɪs.tə.mɪn/ , /ˌæn.taɪˈhɪs.tə.mɪn/

Medical / Technical / Everyday

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Quick answer

What does “antihistamine” mean?

A substance or drug that blocks the effects of histamine in the body, used especially to treat allergy symptoms.

Audio

Pronunciation

Definition

Meaning and Definition

A substance or drug that blocks the effects of histamine in the body, used especially to treat allergy symptoms.

Any compound, typically a medication, that counteracts histamine's action at the histamine receptor sites, providing relief from conditions like hay fever, hives, or motion sickness.

Dialectal Variation

British vs American Usage

Differences

No significant lexical difference in the word itself. Brand names may vary, but the generic term is identical.

Connotations

Neutral in both varieties. Associated with common, often over-the-counter medication.

Frequency

Equally common and understood in both varieties due to global medical terminology.

Grammar

How to Use “antihistamine” in a Sentence

take [an] ANTIHISTAMINE for [condition]be on ANTIHISTAMINES[Drug] is an ANTIHISTAMINE

Vocabulary

Collocations

strong
take an antihistamineprescribe an antihistamineover-the-counter antihistamineoral antihistamine
medium
strong/potent antihistamineantihistamine cream/tabletantihistamine medicationdrowsy/non-drowsy antihistamine
weak
common antihistaminehelpful antihistamineneed an antihistaminebuy an antihistamine

Examples

Examples of “antihistamine” in a Sentence

adjective

British English

  • Take an antihistamine tablet before bed.
  • She needed antihistamine cream for the rash.

American English

  • He recommended an antihistamine medication.
  • The antihistamine effect made her drowsy.

Usage

Meaning in Context

Business

Rare, except in pharmaceutical industry contexts discussing drug portfolios or sales.

Academic

Common in medical, pharmacological, and biological texts discussing immune responses and drug mechanisms.

Everyday

Very common when discussing allergies, cold symptoms, or bites/stings.

Technical

Precise term in medicine and pharmacology, specifying receptor action and drug classifications.

Vocabulary

Synonyms of “antihistamine”

Strong

H1 receptor antagonist (technical)histamine antagonist (technical)

Neutral

allergy pillallergy medicationhistamine blocker

Weak

allergy reliefhay fever tablet

Vocabulary

Antonyms of “antihistamine”

Watch out

Common Mistakes When Using “antihistamine”

  • Mispronunciation: /ˌæn.tiˈhɪs.tə.maɪn/ (incorrect ending).
  • Spelling: 'antihistimine' or 'antihistamine' (missing 'a').
  • Using as a verb: 'I need to antihistamine' (incorrect) vs. 'I need to take an antihistamine'.

FAQ

Frequently Asked Questions

Some older ('first-generation') antihistamines commonly cause drowsiness. Newer ('second-generation') ones are typically non-drowsy, but effects can vary by individual.

Many antihistamines are designed for daily use, especially for managing chronic allergies. However, you should always follow the dosage instructions and consult a doctor for long-term use.

Antihistamines block histamine to relieve symptoms like itching, sneezing, and runny nose. Decongestants shrink swollen blood vessels in the nasal passages to relieve stuffiness. Some medications combine both.

Oral antihistamines typically start working within 30 minutes to 2 hours, with peak effects around 4-6 hours after taking. Some long-acting formulations provide relief for 24 hours.

A substance or drug that blocks the effects of histamine in the body, used especially to treat allergy symptoms.

Antihistamine is usually medical / technical / everyday in register.

Antihistamine: in British English it is pronounced /ˌæn.tiˈhɪs.tə.miːn/, and in American English it is pronounced /ˌæn.tiˈhɪs.tə.mɪn/ , /ˌæn.taɪˈhɪs.tə.mɪn/. Tap the audio buttons above to hear it.

Learning

Memory Aids

Mnemonic

ANTI-HIST-AMINE: Think 'AGAINST-HIST-ory' of allergies. You take an ANTIhistamine to work AGAINST the HISTamine that causes your allergy story.

Conceptual Metaphor

A BLOCKER / SHIELD / CALMING AGENT.

Practice

Quiz

Fill in the gap
My allergies were so bad that I had to before leaving the house.
Multiple Choice

What is the primary function of an antihistamine?