chlorthalidone: meaning, definition, pronunciation and examples
Very LowTechnical/Medical
Quick answer
What does “chlorthalidone” mean?
A thiazide-like diuretic medication used to treat high blood pressure and fluid retention.
Audio
Pronunciation
Definition
Meaning and Definition
A thiazide-like diuretic medication used to treat high blood pressure and fluid retention.
A long-acting sulfonamide-derived drug that inhibits sodium reabsorption in the distal convoluted tubule of the kidney, promoting water excretion and reducing blood volume.
Dialectal Variation
British vs American Usage
Differences
No significant differences in meaning or usage. Spelling is identical. Prescription practices and brand names may vary slightly.
Connotations
Neutral medical term in both varieties.
Frequency
Equally low frequency in both UK and US English, confined to medical professionals, pharmacists, and patients with specific conditions.
Grammar
How to Use “chlorthalidone” in a Sentence
The doctor prescribed [chlorthalidone] for hypertension.[Chlorthalidone] is often combined with other antihypertensives.Patients taking [chlorthalidone] should monitor their potassium.Vocabulary
Collocations
Examples
Examples of “chlorthalidone” in a Sentence
adjective
British English
- The chlorthalidone group showed a significant reduction in systolic pressure.
- A chlorthalidone-based regimen is recommended.
American English
- The chlorthalidone cohort had better outcomes.
- She is on a chlorthalidone prescription.
Usage
Meaning in Context
Business
Not used in general business contexts. May appear in pharmaceutical industry reports or marketing materials.
Academic
Used in medical, pharmacological, and clinical research papers discussing hypertension treatment, comparative drug efficacy, or renal physiology.
Everyday
Virtually never used in casual conversation unless discussing personal medical treatment with a healthcare provider.
Technical
The primary context. Used in patient records, clinical guidelines, pharmacology textbooks, drug formularies, and between healthcare professionals.
Vocabulary
Synonyms of “chlorthalidone”
Strong
Neutral
Weak
Vocabulary
Antonyms of “chlorthalidone”
Watch out
Common Mistakes When Using “chlorthalidone”
- Misspelling as 'chlorothalidone', 'chlorthalidon', or 'clorthalidone'.
- Mispronouncing the 'th' as in 'thin' instead of as in 'the'.
- Using it as a general term for any diuretic.
FAQ
Frequently Asked Questions
No, they are different drugs within the same general class. Chlorthalidone is a thiazide-like diuretic with a longer half-life and greater potency per milligram than hydrochlorothiazide, a true thiazide.
Common side effects include increased urination, dizziness, low blood potassium (hypokalemia), and, less commonly, increased blood sugar or gout flares.
It is generally not recommended during pregnancy, especially in the first and second trimesters, as it may cross the placenta and pose risks to the foetus. A doctor must evaluate the benefits and risks.
Regular blood tests are needed to monitor electrolyte levels (especially potassium and sodium), kidney function, and blood glucose, as the drug can affect all of these.
A thiazide-like diuretic medication used to treat high blood pressure and fluid retention.
Chlorthalidone is usually technical/medical in register.
Chlorthalidone: in British English it is pronounced /klɔːˈθælɪdəʊn/, and in American English it is pronounced /klɔːrˈθælɪdoʊn/. Tap the audio buttons above to hear it.
Learning
Memory Aids
Mnemonic
Think: 'CHLOR' (like chloride, which it affects) + 'THALI' (sounds like 'tally' – to count/measure blood pressure) + 'DONE' (the job is done on hypertension).
Conceptual Metaphor
MEDICATION IS A TOOL (a tool for removing excess fluid and lowering pressure).
Practice
Quiz
Chlorthalidone is primarily classified as what type of drug?