citrate: meaning, definition, pronunciation and examples

C2
UK/ˈsɪtreɪt/US/ˈsɪtreɪt/

Technical/Scientific

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Quick answer

What does “citrate” mean?

A salt or ester of citric acid, a key organic compound found in citrus fruits.

Audio

Pronunciation

Definition

Meaning and Definition

A salt or ester of citric acid, a key organic compound found in citrus fruits.

In biochemistry, a central molecule in the Krebs (citric acid) cycle, which is crucial for cellular energy production. In medicine and industry, citrate salts are used as anticoagulants (e.g., in blood collection tubes), preservatives, and food additives (e.g., acidity regulators).

Dialectal Variation

British vs American Usage

Differences

No significant differences in meaning or usage. Spelling of related words (e.g., analyse/analyze) may differ in respective scientific publications.

Connotations

Identical technical connotations. The verb form 'to citrate' is more common in American medical/pharmaceutical literature.

Frequency

Slightly more frequent in American English due to larger volume of biomedical and pharmaceutical literature.

Grammar

How to Use “citrate” in a Sentence

[N] citrate[ADJ] citratecitrate of [METAL/NAME]to citrate [OBJECT] (verb)

Vocabulary

Collocations

strong
sodium citratecitrate synthasecitrate solutionpotassium citrate
medium
magnesium citrateblood citrateurinary citratecitrate buffer
weak
high citratelow citrateadd citratecontain citrate

Examples

Examples of “citrate” in a Sentence

verb

British English

  • The laboratory protocol requires you to citrate the blood sample immediately.
  • This compound is citrated to enhance its solubility.

American English

  • They had to citrate the plasma to keep it from clotting during the procedure.
  • The formula is citrated for stability.

adjective

British English

  • The citrate concentration was measured spectrophotometrically.
  • We observed a citrate-dependent reaction.

American English

  • The citrate level in the urine was abnormally low.
  • A citrate-based anticoagulant is preferred.

Usage

Meaning in Context

Business

In the pharmaceutical or food additive industry: 'The contract specifies a monthly supply of magnesium citrate.'

Academic

In biochemistry: 'The study measured the inhibitory effect of citrate on the enzyme.'

Everyday

Virtually non-existent. Possible in specific health contexts: 'My doctor recommended potassium citrate for my kidneys.'

Technical

In medicine/lab work: 'The blood samples were collected in citrate tubes to prevent clotting.'

Vocabulary

Synonyms of “citrate”

Neutral

citric acid saltcitrate ester

Weak

acid salt (contextual)chelator (contextual)

Watch out

Common Mistakes When Using “citrate”

  • Mispronouncing as /saɪˈtreɪt/ (like 'sight-rate').
  • Using 'citrate' to mean 'citric acid'.
  • Incorrect pluralisation: 'citrates' is correct for multiple types.

FAQ

Frequently Asked Questions

No. Citric acid is the parent acid (C₆H₈O₇). A citrate is a salt or ester formed when that acid reacts with a base or an alcohol.

Yes, in technical contexts, especially medicine/pharmacy. 'To citrate' means to treat or mix with a citrate, usually to prevent blood coagulation or to adjust solubility.

No. It is a specialist term from chemistry, biology, and medicine. The average person might encounter it on food or medicine labels.

In medicine, 'sodium citrate' is very common as an anticoagulant. In biochemistry, 'citrate synthase' (an enzyme) is a fundamental term.

A salt or ester of citric acid, a key organic compound found in citrus fruits.

Citrate is usually technical/scientific in register.

Citrate: in British English it is pronounced /ˈsɪtreɪt/, and in American English it is pronounced /ˈsɪtreɪt/. Tap the audio buttons above to hear it.

Learning

Memory Aids

Mnemonic

Think of CITRUS fruits (lemons, oranges) which contain CITRIC acid. CITR-ATE is the salt or ester made from that acid.

Conceptual Metaphor

CITRATE IS A KEY / CITRATE IS A REGULATOR (e.g., a key molecule in a cycle; a regulator of acidity or coagulation).

Practice

Quiz

Fill in the gap
Blood for coagulation tests is often collected in tubes containing sodium to prevent clotting.
Multiple Choice

In which of the following contexts is the word 'citrate' MOST likely to be used?

Practise

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