colchicine: meaning, definition, pronunciation and examples

C2+ (Very Low/Technical)
UK/ˈkɒl.tʃɪ.siːn/US/ˈkɑːl.tʃɪˌsiːn/

Medical, Pharmaceutical, Scientific (Botany/Genetics). Highly specialized.

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Quick answer

What does “colchicine” mean?

A toxic organic compound and medication derived from the autumn crocus (Colchicum autumnale), primarily used to treat gout and familial Mediterranean fever.

Audio

Pronunciation

Definition

Meaning and Definition

A toxic organic compound and medication derived from the autumn crocus (Colchicum autumnale), primarily used to treat gout and familial Mediterranean fever.

In botany and genetics, a substance used to inhibit cell division by preventing spindle formation, useful in plant breeding to induce polyploidy.

Dialectal Variation

British vs American Usage

Differences

No significant lexical differences. Pronunciations differ slightly (see IPA).

Connotations

Identical; carries strong connotations of specialized medical/scientific knowledge. In both varieties, laypersons are unlikely to know the term.

Frequency

Extremely low frequency in general discourse, identical in specialized medical/scientific contexts.

Grammar

How to Use “colchicine” in a Sentence

Colchicine is used to treat [disease].The doctor prescribed [dosage] of colchicine.[Subject] is/are taking colchicine for [condition].

Vocabulary

Collocations

strong
prescribe colchicinecolchicine therapycolchicine dosagecolchicine toxicitycolchicine alkaloid
medium
take colchicinerespond to colchicineacute gout colchicinetreatment with colchicineside effects of colchicine
weak
colchicine and probenecidcolchicine for pericarditiscolchicine-induced

Usage

Meaning in Context

Business

Not used.

Academic

Used in pharmacology, medicine, botany, and genetics research papers and textbooks.

Everyday

Virtually never used unless the speaker has a condition like gout.

Technical

The primary context. Precise term in clinical notes, pharmacology, and cytogenetics protocols.

Vocabulary

Synonyms of “colchicine”

Neutral

gout medicationanti-gout agent

Weak

anti-inflammatory (in gout context)

Watch out

Common Mistakes When Using “colchicine”

  • Mispronunciation: /koʊlˈtʃaɪ.siːn/ or /ˈkɒl.kɪ.siːn/.
  • Misspelling: 'colchisin', 'colchacine'.
  • Assuming it is a common painkiller like ibuprofen.

FAQ

Frequently Asked Questions

Its most common medical use is for the treatment and prevention of acute gout flares and familial Mediterranean fever.

Not in the general sense like paracetamol or ibuprofen. It is a specific anti-inflammatory agent that treats the underlying inflammation in conditions like gout, which relieves pain as a result.

No, in most countries, including the UK and US, colchicine is a prescription-only medication due to its potential toxicity and need for precise dosing.

In botany and genetics, colchicine is used in laboratories to induce polyploidy in plants by preventing chromosome segregation during cell division.

A toxic organic compound and medication derived from the autumn crocus (Colchicum autumnale), primarily used to treat gout and familial Mediterranean fever.

Colchicine is usually medical, pharmaceutical, scientific (botany/genetics). highly specialized. in register.

Colchicine: in British English it is pronounced /ˈkɒl.tʃɪ.siːn/, and in American English it is pronounced /ˈkɑːl.tʃɪˌsiːn/. Tap the audio buttons above to hear it.

Learning

Memory Aids

Mnemonic

Think: 'COLD chiropractor SEEs a SINew' -> COLCHICINE is a medicine for the joint pain (sinew) of gout, which can flare up in cold weather.

Conceptual Metaphor

MEDICINE IS A PRECISE TOOL / CHEMICAL IS AN AGENT (e.g., 'Colchicine works by inhibiting microtubule polymerization.').

Practice

Quiz

Fill in the gap
For an acute flare of gout, the rheumatologist decided to initiate a short course of .
Multiple Choice

Colchicine is primarily derived from which plant?

Practise

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