corepressor: meaning, definition, pronunciation and examples

C2 (Very Low Frequency)
UK/ˌkəʊ.rɪˈprɛs.ə/US/ˌkoʊ.rɪˈprɛs.ɚ/

Technical/Scientific (Specialist)

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Quick answer

What does “corepressor” mean?

In molecular biology: a molecule that binds to a repressor protein, enabling it to inhibit gene transcription.

Audio

Pronunciation

Definition

Meaning and Definition

In molecular biology: a molecule that binds to a repressor protein, enabling it to inhibit gene transcription.

Any substance or molecule that works in conjunction with another to suppress or inhibit a biological process, primarily in the context of gene regulation.

Dialectal Variation

British vs American Usage

Differences

No significant lexical or spelling differences. The term is identical in both varieties.

Connotations

No difference in connotation. Purely denotative scientific term.

Frequency

Extremely rare in both varieties, confined entirely to molecular biology, genetics, and biochemistry literature.

Grammar

How to Use “corepressor” in a Sentence

The [SUBSTANCE] acts as a corepressor for the [REPRESSOR PROTEIN].A corepressor binds to and activates the [REPRESSOR].

Vocabulary

Collocations

strong
bind tofunction as arecruit aacts as acomplex with a repressor
medium
small moleculemetabolitetranscriptionalin the presence of
weak
biologicalspecificcellularmolecular

Examples

Examples of “corepressor” in a Sentence

verb

British English

  • The molecule is hypothesised to corepress transcription. (Rare/Non-standard technical use)

American English

  • The metabolite may corepress the operon. (Rare/Non-standard technical use)

adverb

British English

  • N/A

American English

  • N/A

adjective

British English

  • The corepressor function was analysed. (Attributive noun use)

American English

  • Corepressor activity was assayed. (Attributive noun use)

Usage

Meaning in Context

Business

Not used.

Academic

Exclusively used in life sciences research papers, textbooks, and lectures on genetics and molecular biology.

Everyday

Never used.

Technical

The primary context. Used to describe specific molecular mechanisms in gene regulation pathways.

Vocabulary

Synonyms of “corepressor”

Strong

None. This is a specific technical term.

Neutral

repressor complex componenttranscriptional inhibitor (co-factor)

Weak

inhibitory cofactorsuppressor molecule

Vocabulary

Antonyms of “corepressor”

coactivatorinduceractivator

Watch out

Common Mistakes When Using “corepressor”

  • Misspelling as 'co-repressor' with a hyphen (though sometimes accepted) or 'corepresser'.
  • Using it as a verb (e.g., 'to corepress').
  • Confusing it with 'repressor', which is the main protein it assists.

FAQ

Frequently Asked Questions

No, it is a highly specialised term used only in molecular biology and related fields. It is extremely rare in general language.

Standard usage is as a noun. Using it as a verb (e.g., 'to corepress') is non-standard and very rare, even in technical writing. Writers typically use phrases like 'act as a corepressor for' or 'function in corepression'.

A repressor is a protein that can bind to DNA to inhibit gene transcription. A corepressor is a molecule (often not a protein itself) that must bind to the repressor protein to enable it to function. The repressor is the primary actor; the corepressor is its necessary helper.

Yes. In molecular biology, tryptophan in the E. coli trp operon is a classic example. Tryptophan binds to the trp repressor protein, activating it to block transcription of genes involved in tryptophan synthesis.

In molecular biology: a molecule that binds to a repressor protein, enabling it to inhibit gene transcription.

Corepressor is usually technical/scientific (specialist) in register.

Corepressor: in British English it is pronounced /ˌkəʊ.rɪˈprɛs.ə/, and in American English it is pronounced /ˌkoʊ.rɪˈprɛs.ɚ/. Tap the audio buttons above to hear it.

Phrases

Idioms & Phrases

  • None

Learning

Memory Aids

Mnemonic

Think CO-worker + rePRESSOR. A co-worker helps the main repressor protein do its job of pressing down (repressing) gene activity.

Conceptual Metaphor

N/A (Literal technical term).

Practice

Quiz

Fill in the gap
In the lac operon model, allolactose is an inducer, not a .
Multiple Choice

What is the primary role of a corepressor?