What is dacarbazine used for?

It is primarily used to treat metastatic malignant melanoma and Hodgkin's lymphoma.

How is dacarbazine administered?

It is administered intravenously (IV) in a hospital or clinical setting.

What are common side effects of dacarbazine?

Common side effects include nausea, vomiting, bone marrow suppression (lowered blood cell counts), and flu-like symptoms.

Is dacarbazine a brand name?

No, 'dacarbazine' is the generic (non-proprietary) name for the drug. A common brand name was DTIC-Dome.

dacarbazine

Very Low

UK/dəˈkɑːbəziːn/US/dəˈkɑːrbəziːn/

Technical/Medical

My Flashcards

Definition

Meaning

A chemotherapy drug used to treat certain cancers, especially malignant melanoma and Hodgkin's lymphoma.

A synthetic antineoplastic agent belonging to the class of alkylating agents; it interferes with DNA replication and transcription to inhibit cancer cell growth.

Linguistics

Semantic Notes

This is a highly specific pharmaceutical term. Its meaning is fixed and non-figurative. It is known primarily within oncology, pharmacology, and related medical fields.

Dialectal Variation

British vs American Usage

Differences

No significant differences in meaning or usage. Spelling is consistent.

Connotations

Solely denotes the specific pharmaceutical compound; carries the same clinical and technical connotations globally.

Frequency

Extremely low frequency in general discourse but standard within its professional domain in both the UK and US.

Vocabulary

Collocations

strong

intravenous dacarbazinedacarbazine therapydacarbazine treatmentdose of dacarbazine

medium

administer dacarbazinerespond to dacarbazinetolerate dacarbazine

weak

patient received dacarbazineeffect of dacarbazinecycle of dacarbazine

Grammar

Valency Patterns

Patient + receive + dacarbazineOncologist + prescribe + dacarbazineDacarbazine + be + administered + to + patient

Vocabulary

Synonyms

Neutral

DTIC

Weak

chemotherapy drugalkylating agent

Usage

Context Usage

Business

Not used.

Academic

Used in medical and pharmacological research papers discussing cancer treatments.

Everyday

Virtually never used; a patient might hear it from their oncologist.

Technical

Core term in oncology, chemotherapy protocols, and pharmaceutical literature.

Examples

By CEFR Level

The doctor mentioned a medicine called dacarbazine.

Dacarbazine is a chemotherapy drug used for skin cancer.

The treatment protocol involves a combination of dacarbazine and other agents to improve efficacy.

Learning

Memory Aids

Mnemonic

Think: "DECArb" like a car's decal, but it's a drug that 'bars' (inhibits) 'azine' (a chemical suffix) cancer cells.

Conceptual Metaphor

N/A (Highly technical term with no common metaphorical extensions).

Watch out

Common Pitfalls

Translation Traps (for Russian speakers)

Do not confuse with similar-sounding Russian words like "декарбонизация" (decarbonization). The drug's name is a transliteration: "дакарбазин".

Common Mistakes

Misspelling as 'decarbazine' or 'dacarbazin'.
Mispronouncing the stress (correct stress is on the second syllable).

Practice

Quiz

Fill in the gap

For advanced melanoma, the oncologist considered a regimen containing .

Multiple Choice

Dacarbazine is primarily classified as what type of agent?

FAQ

Frequently Asked Questions

: It is primarily used to treat metastatic malignant melanoma and Hodgkin's lymphoma.
: It is administered intravenously (IV) in a hospital or clinical setting.
: Common side effects include nausea, vomiting, bone marrow suppression (lowered blood cell counts), and flu-like symptoms.
: No, 'dacarbazine' is the generic (non-proprietary) name for the drug. A common brand name was DTIC-Dome.