deuterate: meaning, definition, pronunciation and examples

C2 (Very Rare/Specialised)
UK/ˈdjuːtəreɪt/US/ˈduːtəreɪt/

Formal, Technical, Scientific

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Quick answer

What does “deuterate” mean?

To combine or treat (a compound) with deuterium or heavy water, especially by replacing hydrogen atoms with deuterium atoms.

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Pronunciation

Definition

Meaning and Definition

To combine or treat (a compound) with deuterium or heavy water, especially by replacing hydrogen atoms with deuterium atoms.

In chemistry and related sciences, to introduce deuterium (²H, the heavy isotope of hydrogen) into a molecule, often as a method of isotopic labelling for analytical purposes such as NMR spectroscopy or reaction mechanism studies.

Dialectal Variation

British vs American Usage

Differences

No significant difference in meaning or usage. Spelling and pronunciation follow regional norms, but the term itself is international scientific vocabulary.

Connotations

No regional connotations; purely technical.

Frequency

Extremely rare in both varieties outside of specialised scientific literature. Frequency is identical.

Grammar

How to Use “deuterate” in a Sentence

[Subject: Scientist/Process] deuterate [Object: Compound/Molecule] (with [Instrumental: D₂O/deuterium])

Vocabulary

Collocations

strong
to deuterate a compoundto deuterate the sampleto deuterate the solventdeuterated water (D₂O)
medium
attempt to deuteratecompletely deuteratepartially deuterateeasily deuterated
weak
carefully deuteratesuccessfully deuteratecommon to deuterate

Examples

Examples of “deuterate” in a Sentence

verb

British English

  • The researchers needed to deuterate the organic solvent before running the NMR experiment.
  • It's common practice to deuterate the sample to simplify the spectral analysis.

American English

  • The lab will deuterate the compound with D₂O to trace the reaction pathway.
  • They deuterated the methyl group specifically to study its kinetic isotope effect.

adverb

British English

  • The molecule was partially deuterated.
  • The sample was not sufficiently deuterated for clear results.

American English

  • The solvent was fully deuterated prior to the experiment.
  • Specifically deuterated substrates are valuable tools.

adjective

British English

  • The deuterated chloroform was used as the NMR solvent.
  • They analysed the deuterated analogue of the molecule.

American English

  • Deuterated methanol is commercially available for spectroscopic use.
  • The properties of the deuterated compound were compared to the protiated form.

Usage

Meaning in Context

Business

Virtually never used.

Academic

Exclusively used in chemistry, biochemistry, physics, and materials science research papers and textbooks.

Everyday

Never used.

Technical

The primary domain of use. Describes a standard laboratory procedure in spectroscopy and mechanistic studies.

Vocabulary

Synonyms of “deuterate”

Strong

isotopically label with deuteriumsubstitute with deuterium

Neutral

label with deuteriumintroduce deuterium into

Weak

treat with heavy waterprepare a deuterium analogue

Vocabulary

Antonyms of “deuterate”

protonate (in a specific chemical sense)dedeuterate (remove deuterium)

Watch out

Common Mistakes When Using “deuterate”

  • Confusing 'deuterate' (verb) with 'deuterated' (adjective). Incorrect: 'The compound is deuterate.' Correct: 'The compound is deuterated.' or 'They will deuterate the compound.'

FAQ

Frequently Asked Questions

No, it is a highly specialised term used almost exclusively in chemistry and related physical sciences.

'Hydrate' means to combine with water (H₂O). 'Deuterate' specifically means to combine with or introduce deuterium (²H), often using heavy water (D₂O).

Virtually never. Its usage is confined to technical contexts describing isotopic labelling.

The noun form is 'deuteration', as in 'The deuteration of the substrate was confirmed by mass spectrometry.'

To combine or treat (a compound) with deuterium or heavy water, especially by replacing hydrogen atoms with deuterium atoms.

Deuterate is usually formal, technical, scientific in register.

Deuterate: in British English it is pronounced /ˈdjuːtəreɪt/, and in American English it is pronounced /ˈduːtəreɪt/. Tap the audio buttons above to hear it.

Phrases

Idioms & Phrases

  • None

Learning

Memory Aids

Mnemonic

Think of 'DEUTERium' + the verb ending '-ATE' (like 'hydrATE'). It means 'to add DEUTERium'.

Conceptual Metaphor

Not applicable; the term is a literal description of a chemical process.

Practice

Quiz

Fill in the gap
In order to get a cleaner NMR spectrum, the chemist decided to the sample with deuterium oxide.
Multiple Choice

What is the primary purpose of deuterating a compound?

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