diapedesis: meaning, definition, pronunciation and examples

Very low
UK/ˌdaɪəpɪˈdiːsɪs/US/ˌdaɪəpəˈdisɪs/

Technical/Medical

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Quick answer

What does “diapedesis” mean?

The passage of blood cells, especially leukocytes, through the intact walls of capillaries into the surrounding tissue.

Audio

Pronunciation

Definition

Meaning and Definition

The passage of blood cells, especially leukocytes, through the intact walls of capillaries into the surrounding tissue.

A specific process in inflammation and immune response where white blood cells exit the bloodstream to reach sites of infection or injury.

Dialectal Variation

British vs American Usage

Differences

No significant differences in meaning or spelling.

Connotations

None beyond its strict medical definition.

Frequency

Equally rare and specialised in both dialects.

Grammar

How to Use “diapedesis” in a Sentence

The diapedesis of [CELL TYPE]Diapedesis occurs through/into/across [LOCATION]Diapedesis is a critical step in [PROCESS]

Vocabulary

Collocations

strong
leukocyte diapedesisinflammatory diapedesiscapillary diapedesis
medium
process of diapedesisundergo diapedesisinhibit diapedesis
weak
cellular diapedesisvascular diapedesisobserved diapedesis

Usage

Meaning in Context

Business

Not used.

Academic

Core term in medical and life science textbooks and research papers on immunology or inflammation.

Everyday

Virtually never used.

Technical

Precise term in clinical medicine, pathology, and laboratory reports.

Vocabulary

Synonyms of “diapedesis”

Strong

leukocyte extravasation

Vocabulary

Antonyms of “diapedesis”

retentioncontainmentintravascular confinement

Watch out

Common Mistakes When Using “diapedesis”

  • Misspelling as 'diapadesis' or 'diapidesis'.
  • Confusing with 'dialysis' (a different medical process).

FAQ

Frequently Asked Questions

Yes, it is a normal and essential part of the body's immune and inflammatory responses.

Leukocytes (white blood cells), such as neutrophils and monocytes, are the primary cells involved.

Diapedesis is a controlled physiological process of immune cells, while metastasis is the pathological spread of cancer cells through blood vessels.

Yes, but it requires a microscope to observe cells moving through the walls of tiny capillaries in living tissue.

The passage of blood cells, especially leukocytes, through the intact walls of capillaries into the surrounding tissue.

Diapedesis is usually technical/medical in register.

Diapedesis: in British English it is pronounced /ˌdaɪəpɪˈdiːsɪs/, and in American English it is pronounced /ˌdaɪəpəˈdisɪs/. Tap the audio buttons above to hear it.

Learning

Memory Aids

Mnemonic

Dia-pedesis: Think of a DIAmeter (a passage through) and a PEDestrian (a cell) walking through the capillary wall.

Conceptual Metaphor

The white blood cells are like soldiers exiting their transport vehicles (blood vessels) to patrol the tissue neighbourhood.

Practice

Quiz

Fill in the gap
During the inflammatory response, neutrophils undergo to reach the site of tissue damage.
Multiple Choice

What is the primary function of diapedesis?