digoxin: meaning, definition, pronunciation and examples

Low-frequency, Technical
UK/dɪˈdʒɒk.sɪn/US/dɪˈdʒɑːk.sɪn/

Formal, Medical/Technical

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Quick answer

What does “digoxin” mean?

A medication derived from the foxglove plant (Digitalis lanata), used to treat certain heart conditions, such as atrial fibrillation and heart failure, by increasing the strength of heart muscle contractions and slowing the heart rate.

Audio

Pronunciation

Definition

Meaning and Definition

A medication derived from the foxglove plant (Digitalis lanata), used to treat certain heart conditions, such as atrial fibrillation and heart failure, by increasing the strength of heart muscle contractions and slowing the heart rate.

In medical contexts, refers specifically to a purified cardiac glycoside. Outside strict medical use, it can be referenced in discussions of pharmacology, toxicology (due to its narrow therapeutic window), and medical history.

Dialectal Variation

British vs American Usage

Differences

No significant differences in meaning or use. Both varieties use the International Nonproprietary Name (INN) 'digoxin'. The brand name 'Lanoxin' is also recognized in both regions.

Connotations

Purely clinical and precise. Carries connotations of careful dosing, potential toxicity, and chronic heart disease management.

Frequency

Equally low-frequency and restricted to medical contexts in both regions.

Grammar

How to Use “digoxin” in a Sentence

The doctor prescribed digoxin FOR the patient.The patient is ON digoxin.We need to MEASURE the digoxin level.The toxicity was CAUSED BY digoxin.

Vocabulary

Collocations

strong
prescribe digoxindigoxin leveldigoxin toxicitytherapeutic digoxinserum digoxinmaintenance dose of digoxindigoxin overdose
medium
take digoxinon digoxindigoxin therapymonitor digoxininteraction with digoxin
weak
heart digoxinmedicine digoxindrug digoxin

Examples

Examples of “digoxin” in a Sentence

verb

British English

  • [Not applicable. It is a noun.]

American English

  • [Not applicable. It is a noun.]

adverb

British English

  • [Not applicable.]

American English

  • [Not applicable.]

adjective

British English

  • The digoxin assay results are pending.
  • She presented with digoxin toxicity.

American English

  • The digoxin level was within the therapeutic range.
  • He had classic digoxin toxicity symptoms.

Usage

Meaning in Context

Business

Rare, except in pharmaceutical manufacturing, distribution, or healthcare economics reports.

Academic

Common in medical, pharmacology, nursing, and physiology textbooks, research papers, and lectures.

Everyday

Virtually never used in everyday conversation unless a patient or caregiver is discussing a specific treatment regimen.

Technical

The primary context. Used in clinical notes, prescriptions, drug manuals, and communication between healthcare professionals.

Vocabulary

Synonyms of “digoxin”

Strong

Digitalis (the plant genus source, sometimes used for related drugs like digitoxin)

Neutral

cardiac glycosideLanoxin (brand name)

Weak

heart medicationpill for the heart

Vocabulary

Antonyms of “digoxin”

digoxin antidote (Digibind/digoxin immune fab)beta-blocker (has opposite effect on heart rate in some contexts)

Watch out

Common Mistakes When Using “digoxin”

  • Mispronouncing it as /daɪˈɡɒk.sɪn/ (with a hard 'g').
  • Confusing it with 'digitoxin' (a different, older glycoside).
  • Using it as a general term for heart medicine.
  • Misspelling as 'digoxine'.

FAQ

Frequently Asked Questions

Digitalis is the name of the plant genus (foxglove). Digoxin is one specific chemical compound (a cardiac glycoside) purified from Digitalis lanata. 'Digitalis' is sometimes used historically to refer to the leaf powder or other compounds like digitoxin.

Digoxin has a very narrow therapeutic window. This means the difference between a helpful dose and a toxic, dangerous dose is very small. Factors like kidney function, other medications, and age can easily push levels out of the safe range.

Symptoms include gastrointestinal issues (nausea, vomiting, diarrhoea), visual disturbances (blurred vision, yellow/green halos), confusion, and potentially dangerous heart rhythm abnormalities.

No. Abruptly stopping digoxin, especially for conditions like heart failure or atrial fibrillation, can lead to a worsening of the underlying heart condition. Any change in dosage must be done under direct medical supervision.

A medication derived from the foxglove plant (Digitalis lanata), used to treat certain heart conditions, such as atrial fibrillation and heart failure, by increasing the strength of heart muscle contractions and slowing the heart rate.

Digoxin is usually formal, medical/technical in register.

Digoxin: in British English it is pronounced /dɪˈdʒɒk.sɪn/, and in American English it is pronounced /dɪˈdʒɑːk.sɪn/. Tap the audio buttons above to hear it.

Phrases

Idioms & Phrases

  • [None. Technical term does not feature in idioms.]

Learning

Memory Aids

Mnemonic

Imagine a DJ (the 'dig' sound) wearing an OX mask (ox) and giving an INjection. The DJ-OX-IN is a strong medicine for the heart.

Conceptual Metaphor

Not applicable. It is a concrete substance.

Practice

Quiz

Fill in the gap
Because of its narrow therapeutic index, patients taking checked regularly.
Multiple Choice

What is the primary source of digoxin?

digoxin: meaning, definition, pronunciation and examples | Lingvocore