gene clone: meaning, definition, pronunciation and examples

C2
UK/dʒiːn kləʊn/US/dʒin kloʊn/

Technical/Scientific

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Quick answer

What does “gene clone” mean?

A genetically identical copy of a particular gene or DNA sequence, produced through laboratory techniques.

Audio

Pronunciation

Definition

Meaning and Definition

A genetically identical copy of a particular gene or DNA sequence, produced through laboratory techniques.

The process of creating such a copy, or the collective copies (a gene library) containing the target sequence.

Dialectal Variation

British vs American Usage

Differences

No significant lexical or spelling differences. Pronunciation of 'gene' may vary slightly.

Connotations

Identical technical connotations in both varieties.

Frequency

Used with equal frequency in relevant scientific fields in both regions.

Grammar

How to Use “gene clone” in a Sentence

The [scientist] [created] a gene clone of [the insulin gene].

Vocabulary

Collocations

strong
isolate acreate aobtain aidentify ascreen ause agenerate a
medium
successfulspecificfunctionalbacterialrecombinantcompleteexact
weak
potentialnoveldesiredmutanttherapeutic

Examples

Examples of “gene clone” in a Sentence

verb

British English

  • The team aimed to clone the gene responsible for the trait.
  • We need to clone this fragment before sequencing.

American English

  • The lab successfully cloned the drought-resistance gene.
  • The first step is to clone the DNA segment into a plasmid.

adverb

British English

  • [Not typically used as an adverb]

American English

  • [Not typically used as an adverb]

adjective

British English

  • The gene clone library was screened for positives.
  • Clone DNA was purified for further analysis.

American English

  • The gene clone sequence was verified.
  • Clone purification is a standard step.

Usage

Meaning in Context

Business

Rare, except in biotech/pharma contexts discussing product development.

Academic

Core term in genetics, molecular biology, and biotechnology papers and textbooks.

Everyday

Virtually never used in general conversation.

Technical

Fundamental and frequent term describing a key laboratory product and process.

Vocabulary

Synonyms of “gene clone”

Strong

cloned DNA fragmentamplified gene sequence

Neutral

DNA clonegenetic clone

Vocabulary

Antonyms of “gene clone”

wild-type gene (in its original, uncloned state)

Watch out

Common Mistakes When Using “gene clone”

  • Using 'clone' alone to refer to the gene copy without specifying 'gene' in introductory contexts.
  • Using as a verb in the phrase ('They gene cloned the sequence' is less standard than 'They cloned the gene').

FAQ

Frequently Asked Questions

No. A 'gene clone' refers to a copy of a specific DNA sequence (e.g., in a test tube or bacterial cell). A 'cloned organism' (like Dolly the sheep) is a whole organism that is genetically identical to another.

The primary tool is molecular cloning, which often involves inserting the target DNA into a bacterial plasmid (a circular DNA vector), which is then used to transform bacteria. The bacteria then replicate the plasmid, producing many identical copies—the gene clone.

While 'clone' is the verb ('to clone a gene'), the full phrase 'gene clone' is almost exclusively a noun. You would say 'They cloned the gene', not 'They gene cloned it'.

It is a foundational term in molecular biology, genetics, genetic engineering, biotechnology, and related biomedical research fields.

A genetically identical copy of a particular gene or DNA sequence, produced through laboratory techniques.

Gene clone is usually technical/scientific in register.

Gene clone: in British English it is pronounced /dʒiːn kləʊn/, and in American English it is pronounced /dʒin kloʊn/. Tap the audio buttons above to hear it.

Phrases

Idioms & Phrases

  • [Not applicable for this technical term]

Learning

Memory Aids

Mnemonic

Think of a 'gene clone' as a genetic twin created in a lab – an identical copy of a single gene.

Conceptual Metaphor

COPYING/REPLICATION: A gene clone is conceptualised as a copy, a duplicate, or a replica of an original genetic blueprint.

Practice

Quiz

Fill in the gap
Researchers must first create a stable before they can study the function of an unknown DNA sequence in detail.
Multiple Choice

What is the primary purpose of creating a 'gene clone'?