glyoxylate: meaning, definition, pronunciation and examples

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UK/ɡlaɪˈɒksɪleɪt/US/ɡlaɪˈɑːksɪleɪt/

Technical/Scientific

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Quick answer

What does “glyoxylate” mean?

A salt or ester of glyoxylic acid, an organic compound with the formula OCHCO₂⁻.

Audio

Pronunciation

Definition

Meaning and Definition

A salt or ester of glyoxylic acid, an organic compound with the formula OCHCO₂⁻.

In biochemistry, it refers to the anion or any compound containing the glyoxylate group, central to the glyoxylate cycle—a metabolic pathway in plants, bacteria, and fungi that allows conversion of fats into carbohydrates.

Dialectal Variation

British vs American Usage

Differences

No significant differences in meaning or usage. Spelling follows the same pattern.

Connotations

None beyond its strict scientific definition.

Frequency

Equally rare in both dialects, confined to specialised literature.

Grammar

How to Use “glyoxylate” in a Sentence

The enzyme converts X into glyoxylate.Glyoxylate is a key intermediate in Y.

Vocabulary

Collocations

strong
glyoxylate cycleglyoxylate pathwayisocitrate lyasemalate synthase
medium
metabolize glyoxylateglyoxylate shuntglyoxylate metabolism
weak
glyoxylate concentrationglyoxylate productionglyoxylate accumulation

Examples

Examples of “glyoxylate” in a Sentence

verb

British English

  • The bacterium can glyoxylate fatty acids to support growth on acetate.

American English

  • The engineered yeast strain was designed to glyoxylate two-carbon units efficiently.

adverb

British English

  • N/A

American English

  • N/A

adjective

British English

  • The glyoxylate shunt activity was measured in the cell extract.

American English

  • Researchers identified a key glyoxylate pathway enzyme.

Usage

Meaning in Context

Business

Not used.

Academic

Used in advanced biochemistry, microbiology, and plant science papers and textbooks.

Everyday

Never used.

Technical

Core term in describing the glyoxylate cycle and related enzymatic reactions in organisms like bacteria, fungi, and germinating seeds.

Vocabulary

Synonyms of “glyoxylate”

Strong

glyoxylate ion

Neutral

glyoxylic acid salt

Weak

oxoacetate (in specific contexts)

Vocabulary

Antonyms of “glyoxylate”

N/A (highly specific chemical term)

Watch out

Common Mistakes When Using “glyoxylate”

  • Misspelling as 'glyoxalate' (incorrect).
  • Confusing the 'glyoxylate cycle' with the 'citric acid cycle' (Krebs cycle).
  • Using it as a general term instead of its specific biochemical meaning.

FAQ

Frequently Asked Questions

It enables organisms like plants and bacteria to convert acetyl-CoA derived from fats into four-carbon compounds (like malate) for gluconeogenesis, allowing them to make sugars from fats.

No. Glyoxylic acid is the parent acid (HOOC-CHO). Glyoxylate is its conjugate base (anion) or its salt/ester form.

Animals lack the two key enzymes, isocitrate lyase and malate synthase, so they cannot perform this net conversion of fats to carbohydrates.

Virtually nowhere in everyday life. It is a specialist term found in advanced biochemistry textbooks, research papers on metabolism, and microbiology contexts.

A salt or ester of glyoxylic acid, an organic compound with the formula OCHCO₂⁻.

Glyoxylate is usually technical/scientific in register.

Glyoxylate: in British English it is pronounced /ɡlaɪˈɒksɪleɪt/, and in American English it is pronounced /ɡlaɪˈɑːksɪleɪt/. Tap the audio buttons above to hear it.

Phrases

Idioms & Phrases

  • N/A

Learning

Memory Aids

Mnemonic

Think 'GLY' (like glucose/glycolysis) + 'OXY' (oxygen/oxidation) + 'LATE' (arriving later in the metabolic pathway). It's a late-stage, oxygen-involved compound in sugar metabolism.

Conceptual Metaphor

A metabolic bypass or shortcut: The glyoxylate cycle is often described as a 'shunt' allowing organisms to bypass steps of the standard Krebs cycle to build sugars from fats.

Practice

Quiz

Fill in the gap
In the glyoxylate cycle, the enzyme malate synthase condenses with acetyl-CoA to form malate.
Multiple Choice

In which organisms is the glyoxylate cycle primarily active?