goblet cell: meaning, definition, pronunciation and examples

Low
UK/ˈɡɒblət sel/US/ˈɡɑːblət sel/

Technical/Scientific

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Quick answer

What does “goblet cell” mean?

A specialized, mucus-secreting epithelial cell found in the linings of various organs.

Audio

Pronunciation

Definition

Meaning and Definition

A specialized, mucus-secreting epithelial cell found in the linings of various organs.

A columnar epithelial cell, shaped like a goblet, that produces and secretes mucin, a key component of mucus, to protect and lubricate epithelial surfaces. They are abundant in the respiratory and gastrointestinal tracts.

Dialectal Variation

British vs American Usage

Differences

No significant differences in spelling, meaning, or usage between British and American English in technical contexts.

Connotations

Purely technical and neutral in both varieties.

Frequency

Used exclusively in medical, biological, and histological contexts in both regions. Frequency is identical and tied to specialist discourse.

Grammar

How to Use “goblet cell” in a Sentence

The [epithelium] contains goblet cells.Goblet cells secrete [mucin/mucus].An increase in goblet cells is seen in [condition].

Vocabulary

Collocations

strong
intestinal goblet cellrespiratory goblet cellmucus-secreting goblet cellgoblet cell hyperplasia
medium
contains goblet cellslined with goblet cellspopulation of goblet cellsgoblet cell count
weak
numerous goblet cellstypical goblet cellsingle goblet cellnormal goblet cell

Examples

Examples of “goblet cell” in a Sentence

adjective

British English

  • The goblet-cell density was measured.
  • A goblet-cell-specific marker.

American English

  • The goblet cell density was measured.
  • A goblet cell-specific marker.

Usage

Meaning in Context

Business

Not used.

Academic

Core term in histology, physiology, and medical studies related to epithelial biology and mucosal defense.

Everyday

Virtually never used in everyday conversation.

Technical

Precise term in medical diagnostics, pathology (e.g., goblet cell carcinoid), and biological research.

Vocabulary

Synonyms of “goblet cell”

Strong

mucous cell

Neutral

mucus-secreting cell

Weak

secretory epithelial cell

Vocabulary

Antonyms of “goblet cell”

ciliated cellabsorptive cellparietal cell

Watch out

Common Mistakes When Using “goblet cell”

  • Mispronouncing 'goblet' as /ɡoʊˈbleɪ/ (like 'goblay').
  • Using it as a general term for any secretory cell.
  • Misspelling as 'goblin cell' or 'goblet sell'.

FAQ

Frequently Asked Questions

No, it is a single-celled exocrine gland, often called a unicellular gland, but not a multi-cellular gland.

Its primary function is to synthesize and secrete mucin, which hydrates and forms a protective mucus layer on epithelial surfaces.

Yes, in properly stained tissue sections (e.g., with Alcian blue or PAS stain), goblet cells are clearly visible due to their distinctive shape and stained secretory granules.

An increase, called hyperplasia, is often a pathological response to chronic irritation (e.g., in asthma or bronchitis) and can lead to excessive mucus production.

A specialized, mucus-secreting epithelial cell found in the linings of various organs.

Goblet cell is usually technical/scientific in register.

Goblet cell: in British English it is pronounced /ˈɡɒblət sel/, and in American English it is pronounced /ˈɡɑːblət sel/. Tap the audio buttons above to hear it.

Learning

Memory Aids

Mnemonic

Imagine a **goblet** (a fancy cup) being filled with sticky mucus. The cell stores its secretion in a cup-like shape before releasing it.

Conceptual Metaphor

THE CELL IS A CONTAINER (specifically, a cup/goblet holding secretory product).

Practice

Quiz

Fill in the gap
The in the intestinal epithelium secrete mucin to lubricate the surface.
Multiple Choice

Where are goblet cells primarily found?