guanylic acid: meaning, definition, pronunciation and examples

C2 (Very Low Frequency - Technical/Specialist)
UK/ɡwæˌnɪlɪk ˈæsɪd/US/ɡwɑːˌnɪlɪk ˈæsɪd/

Scientific/Technical/Biochemical

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Quick answer

What does “guanylic acid” mean?

A nucleotide constituent of RNA, formed from guanine, ribose, and phosphate.

Audio

Pronunciation

Definition

Meaning and Definition

A nucleotide constituent of RNA, formed from guanine, ribose, and phosphate; specifically guanosine monophosphate (GMP).

An important nucleotide that functions as a building block for RNA and is also involved in cellular signaling as a second messenger (cyclic GMP), playing roles in metabolism, vision, and vasodilation.

Dialectal Variation

British vs American Usage

Differences

No significant differences in usage or spelling. The term is standard in international scientific English.

Connotations

Neutral, purely technical term in both varieties.

Frequency

Equally rare and specialized in both UK and US English, confined to academic and industrial contexts.

Grammar

How to Use “guanylic acid” in a Sentence

Guanylic acid is synthesized from...The addition of guanylic acid to...... contains guanylic acid as a component.Guanylic acid acts as a...The concentration of guanylic acid...Hydrolysis yields guanylic acid.

Vocabulary

Collocations

strong
ribonucleotideguanosine monophosphate (GMP)inosinic aciddisodium guanylateflavor enhancer
medium
solution of guanylic acidsynthesis of guanylic acidderivative of guanylic acidcyclic guanylic acid (cGMP)
weak
pure guanylic acidacidic conditionsnucleotide compositionbiochemical pathway

Examples

Examples of “guanylic acid” in a Sentence

adjective

British English

  • The guanylic acid concentration was measured.
  • A guanylic acid derivative was synthesised.

American English

  • The guanylic acid pathway is crucial.
  • A guanylic acid solution was prepared.

Usage

Meaning in Context

Business

Potentially in the context of food additive manufacturing or biotech patents.

Academic

Primary context. Used in biochemistry, genetics, and molecular biology textbooks and research papers.

Everyday

Virtually never used, except perhaps on detailed ingredient lists for processed foods.

Technical

Core context. Precise term in laboratory protocols, scientific descriptions, and pharmaceutical documentation.

Vocabulary

Synonyms of “guanylic acid”

Strong

5'-guanylic acidguanosine 5'-monophosphate

Weak

guanylate (salt form)ribonucleotide G

Watch out

Common Mistakes When Using “guanylic acid”

  • Misspelling as 'guanylic' (missing 'c') or 'guanilic'.
  • Confusing it with 'guano' (bird droppings) due to phonetic similarity.
  • Using it as a countable noun (e.g., 'three guanylic acids') instead of an uncountable/mass noun.

FAQ

Frequently Asked Questions

No. Monosodium glutamate (MSG) is a different compound. However, guanylic acid (as disodium guanylate) is often used in combination with MSG to synergistically enhance umami flavor.

GMP stands for Guanosine Monophosphate. This is the full biochemical name for guanylic acid.

Yes. It is a fundamental nucleotide produced by all living cells as part of RNA synthesis and metabolic processes.

It serves two major roles: 1) as a monomeric unit for constructing RNA molecules, and 2) in its cyclic form (cGMP), as a vital secondary messenger regulating processes like vision, blood flow, and nerve signal transduction.

A nucleotide constituent of RNA, formed from guanine, ribose, and phosphate.

Guanylic acid is usually scientific/technical/biochemical in register.

Guanylic acid: in British English it is pronounced /ɡwæˌnɪlɪk ˈæsɪd/, and in American English it is pronounced /ɡwɑːˌnɪlɪk ˈæsɪd/. Tap the audio buttons above to hear it.

Learning

Memory Aids

Mnemonic

Think: GUANine + rIBose + phosPhoric ACID = GUANYLIC ACID. It's the 'G' in the RNA alphabet (A, U, C, G).

Conceptual Metaphor

A BUILDING BLOCK or LETTER in the genetic alphabet; a MESSENGER in cellular communication.

Practice

Quiz

Fill in the gap
In molecular biology, the nucleotide , also known as GMP, pairs with cytidine in RNA.
Multiple Choice

In what primary context would you encounter the term 'guanylic acid'?