hematoxylin: meaning, definition, pronunciation and examples

C2
UK/ˌhiːməˈtɒksɪlɪn/US/ˌhɛməˈtɑːksəlɪn/

Technical / Scientific

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Quick answer

What does “hematoxylin” mean?

A natural dye extracted from logwood, used primarily as a nuclear stain in histology and pathology.

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Pronunciation

Definition

Meaning and Definition

A natural dye extracted from logwood, used primarily as a nuclear stain in histology and pathology.

A benzoid compound forming the basis of numerous histological stains, notably in combination with eosin (H&E) to differentiate cellular components under a microscope.

Dialectal Variation

British vs American Usage

Differences

No significant difference in meaning or application. Spelling varies: British 'haematoxylin', American 'hematoxylin'.

Connotations

None beyond its scientific function.

Frequency

Equally common in biomedical literature of both regions, matching the frequency of 'haemoglobin' vs 'hemoglobin' spelling conventions.

Grammar

How to Use “hematoxylin” in a Sentence

[Substance] is stained *with* hematoxylinHematoxylin *is used to* stain nucleiHematoxylin *in combination with* eosin

Vocabulary

Collocations

strong
Harris hematoxylinMayer's hematoxylinhematoxylin and eosin (H&E)hematoxylin stainingalum hematoxylin
medium
counterstain with hematoxylinsolution of hematoxylinsections were stained with hematoxylin
weak
blue hematoxylincommercial hematoxylinfresh hematoxylin

Examples

Examples of “hematoxylin” in a Sentence

adjective

British English

  • The haematoxylin-stained nuclei appeared deep blue.
  • A standard haematoxylin-eosin protocol was followed.

American English

  • The hematoxylin-stained nuclei appeared deep blue.
  • A standard hematoxylin-eosin protocol was followed.

Usage

Meaning in Context

Academic

Ubiquitous in biomedical research papers, histology textbooks, and pathology reports.

Everyday

Never used in everyday conversation.

Technical

Core term in histotechnology, pathology, cell biology, and diagnostic laboratories.

Vocabulary

Synonyms of “hematoxylin”

Strong

haematoxylin (UK spelling)

Neutral

logwood extract

Weak

nuclear stainbasic dye

Vocabulary

Antonyms of “hematoxylin”

eosin (as a counterstain)

Watch out

Common Mistakes When Using “hematoxylin”

  • Misspelling as 'hematoxilyn', 'hemotoxilin', or 'haemotoxilin'.
  • Using it as a verb (e.g., 'to hematoxylin the tissue').

FAQ

Frequently Asked Questions

Rarely. It is almost always used in a formulated stain (e.g., Harris's, Mayer's) and typically followed by a counterstain like eosin.

No, they are the same substance. 'Haematoxylin' is the British English spelling, while 'hematoxylin' is the American English spelling.

Hematoxylin stains basophilic structures, particularly cell nuclei, a purplish-blue colour.

It is a natural product extracted from the heartwood of the logwood tree (Haematoxylum campechianum).

A natural dye extracted from logwood, used primarily as a nuclear stain in histology and pathology.

Hematoxylin is usually technical / scientific in register.

Hematoxylin: in British English it is pronounced /ˌhiːməˈtɒksɪlɪn/, and in American English it is pronounced /ˌhɛməˈtɑːksəlɪn/. Tap the audio buttons above to hear it.

Learning

Memory Aids

Mnemonic

Think: 'HEMA' (like haemoglobin, relating to blood/biology) + 'TOX' (from the logwood *Haematoxylon*) + 'YLIN' (a common chemical suffix).

Practice

Quiz

Fill in the gap
In standard histology, nuclei are typically stained blue with , while cytoplasm is counterstained pink with eosin.
Multiple Choice

In which field is the term 'hematoxylin' primarily used?