heme: meaning, definition, pronunciation and examples

C2
UK/hiːm/US/hiːm/

Academic, Technical, Scientific

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Quick answer

What does “heme” mean?

The deep red, iron-containing component of hemoglobin and other proteins in the blood, which binds to and transports oxygen.

Audio

Pronunciation

Definition

Meaning and Definition

The deep red, iron-containing component of hemoglobin and other proteins in the blood, which binds to and transports oxygen.

In broader biological contexts, it refers to the iron-protoporphyrin complex that serves as a prosthetic group in various hemoproteins, crucial for processes like electron transfer and catalysis.

Dialectal Variation

British vs American Usage

Differences

Spelling: 'haem' is standard in British English (e.g., haemoglobin). 'Heme' is standard in American English.

Connotations

None. Purely scientific denotation.

Frequency

Equally frequent within their respective scientific/medical registers. Virtually non-existent in everyday conversation.

Grammar

How to Use “heme” in a Sentence

[The] heme [in/of something] binds/catalyses...[Verb] heme biosynthesis/pathway

Vocabulary

Collocations

strong
heme groupheme ironheme proteinheme biosynthesisheme oxygenase
medium
bound to hemecontaining hemeheme moleculeheme complex
weak
free hemeheme deficiencyheme metabolism

Examples

Examples of “heme” in a Sentence

adjective

British English

  • The haem-containing protein is essential.
  • Haem biosynthesis is regulated.

American English

  • The heme-containing protein is essential.
  • Heme biosynthesis is regulated.

Usage

Meaning in Context

Business

Not used.

Academic

Central term in biochemistry, physiology, and medicine. Used in research papers and textbooks.

Everyday

Extremely rare. Might appear in advanced health/nutrition contexts (e.g., 'heme iron vs non-heme iron').

Technical

Fundamental term in hematology, enzymology, and molecular biology.

Vocabulary

Synonyms of “heme”

Strong

haem (UK)

Neutral

iron-protoporphyrinheme prosthetic group

Weak

porphyrin complex (broader category)

Vocabulary

Antonyms of “heme”

non-heme iron

Watch out

Common Mistakes When Using “heme”

  • Misspelling as 'heam' or 'heeme'.
  • Incorrectly using 'heme' as a general term for blood.
  • Pronouncing it like 'hem' (edge of cloth) /hɛm/.

FAQ

Frequently Asked Questions

Yes, they refer to the same biochemical compound. 'Heme' is the American English spelling, while 'haem' is the British English spelling.

It is very rare. The closest would be in a nutrition context: 'Red meat is a good source of heme iron, which is more bioavailable.'

Its primary function is to bind oxygen in haemoglobin and myoglobin, enabling oxygen transport and storage in the body. It also serves as a cofactor in various enzymes for electron transfer and catalysis.

It is primarily a noun. It can function attributively as a noun adjunct in compounds like 'heme protein' (functioning similarly to an adjective).

The deep red, iron-containing component of hemoglobin and other proteins in the blood, which binds to and transports oxygen.

Heme is usually academic, technical, scientific in register.

Heme: in British English it is pronounced /hiːm/, and in American English it is pronounced /hiːm/. Tap the audio buttons above to hear it.

Learning

Memory Aids

Mnemonic

Think: HEME helps blood be HEMoglobin. The 'HEM' is the same.

Conceptual Metaphor

None applicable; it is a concrete biochemical entity.

Practice

Quiz

Fill in the gap
The red colour of blood is primarily due to the group within haemoglobin.
Multiple Choice

In which context would you most likely encounter the word 'heme'?

heme: meaning, definition, pronunciation and examples | Lingvocore