hydrolase

C2
UK/ˈhaɪ.drə.leɪz/US/ˈhaɪ.drə.leɪs/

Technical/Scientific

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Definition

Meaning

Any enzyme that catalyzes the hydrolysis of a chemical bond.

A broad class of enzymes that break down molecules by adding water, essential in digestion, metabolism, and various industrial processes.

Linguistics

Semantic Notes

The term is a functional classification (describing what the enzyme does) rather than a structural one. Often forms part of a specific enzyme name (e.g., lactase, protease).

Dialectal Variation

British vs American Usage

Differences

No significant differences in meaning or usage. Spelling and pronunciation are consistent.

Connotations

None beyond the strict scientific definition.

Frequency

Equally rare in general language, used exclusively in biochemistry, biology, and related technical fields in both regions.

Vocabulary

Collocations

strong
enzymehydrolysiscatalysesubstrateactive site
medium
classreactiondigestivespecificmechanism
weak
importantbiologicalcellularfunctiontype

Grammar

Valency Patterns

[hydrolase] + [preposition] + [noun phrase] (e.g., hydrolase acting on esters)[specific] + [hydrolase] (e.g., glycoside hydrolase)[hydrolase] + [enzyme commission number] (e.g., hydrolase EC 3.2.1.1)

Vocabulary

Synonyms

Neutral

hydrolytic enzyme

Weak

digestive enzyme (context-specific)

Vocabulary

Antonyms

synthaseligasepolymerase

Usage

Context Usage

Business

Rare. Might appear in biotech/pharma reports (e.g., 'The company is developing a novel hydrolase for industrial cleaning.')

Academic

Primary context. Common in biochemistry, molecular biology, and pharmacology textbooks and research papers.

Everyday

Virtually never used.

Technical

Standard term in laboratory manuals, enzyme catalogs, and process descriptions in biotechnology.

Examples

By Part of Speech

verb

British English

  • The protein was hydrolased by the enzyme mixture.
  • Researchers aim to hydrolase the polymer efficiently.

American English

  • The protein was hydrolyzed by the enzyme mixture.
  • Researchers aim to hydrolyze the polymer efficiently.

adverb

British English

  • The bond was cleaved hydrolatically (rare).

American English

  • The bond was cleaved hydrolytically.

adjective

British English

  • The hydrolase activity was measured spectrophotometrically.
  • A key hydrolase function is peptide bond cleavage.

American English

  • The hydrolytic activity was measured spectrophotometrically.
  • A key hydrolytic function is peptide bond cleavage.

Examples

By CEFR Level

B2
  • Lactase is a hydrolase that breaks down milk sugar.
  • Many digestive enzymes belong to the hydrolase family.
C1
  • The novel glycoside hydrolase exhibited remarkable thermal stability.
  • The mechanism proceeds via a covalent hydrolase-substrate intermediate.

Learning

Memory Aids

Mnemonic

Think: HYDRO (water) + LASE (like 'erase' or 'amylase'). A hydrolase 'erases' bonds using water.

Conceptual Metaphor

A molecular pair of scissors that uses water as its cutting fluid.

Watch out

Common Pitfalls

Translation Traps (for Russian speakers)

  • Do not confuse with 'гидролаза' (the direct equivalent, correct). Avoid calquing as 'водная лазер' (water laser) or similar nonsense.

Common Mistakes

  • Mispronouncing the final syllable as '-lace' (like the fabric) instead of '-laze/lace' (like 'amylase').
  • Using it as a general term for any enzyme.

Practice

Quiz

Fill in the gap
A is an enzyme that catalyzes the breaking of a bond using water.
Multiple Choice

Which of the following is a hydrolase?

FAQ

Frequently Asked Questions

No, it is a broad class or category of enzymes that share the same function (catalyzing hydrolysis). Specific examples include amylase, lipase, and protease.

The suffix '-ase' is used to form the names of enzymes. It indicates that the word refers to a protein catalyst.

It is highly unlikely and would sound very technical. In everyday contexts, you would use the name of a specific enzyme (e.g., 'lactase' for digesting lactose) or a general term like 'digestive enzyme'.

The opposite action is condensation or synthesis, where a bond is formed with the release of a water molecule. Enzymes that catalyze such reactions are often synthases or ligases.