isomerase

C1
UK/ʌɪˈsɒməreɪz/US/aɪˈsɑːməreɪs/

Formal/Technical (Scientific)

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Definition

Meaning

An enzyme that catalyzes the conversion of a molecule into one of its isomers.

In a broader, metaphorical sense, it can refer to any agent or process that facilitates a structural change while maintaining the same fundamental components.

Linguistics

Semantic Notes

Specifically denotes a class of enzymes in biochemistry. The '-ase' suffix is a clear marker of an enzyme, following the standard biochemical naming convention.

Dialectal Variation

British vs American Usage

Differences

No significant differences in meaning, spelling, or pronunciation.

Connotations

None beyond its strict technical meaning.

Frequency

Exclusively used in scientific contexts (biochemistry, molecular biology) in both regions. No discernible difference in frequency of use.

Vocabulary

Collocations

strong
DNA isomeraseenzymatic isomerasecis-trans isomeraseprostaglandin isomerase
medium
specific isomerasecatalyze isomerasefunction of isomeraserequires isomerase
weak
active isomerasepure isomeraserecombinant isomerasestudy isomerase

Grammar

Valency Patterns

[Enzyme] isomerase + catalyzes + [conversion/reaction][Specific] + isomerase + is + essential for + [process]

Vocabulary

Synonyms

Strong

epimeraseracemase

Neutral

catalytic enzymeisomerizing enzyme

Weak

convertermodifier

Vocabulary

Antonyms

inhibitorstabilizer

Phrases

Idioms & Phrases

  • None. The term is purely technical.

Usage

Context Usage

Business

Virtually never used, except in highly specialized biotech/pharma R&D contexts.

Academic

Core term in biochemistry, molecular biology, genetics, and related life sciences.

Everyday

Not used in everyday conversation.

Technical

A fundamental technical term. Common in research papers, lab protocols, and scientific discussions about metabolic pathways, DNA repair, or stereochemistry.

Examples

By Part of Speech

verb

British English

  • This compound is isomerised by the enzyme.
  • The pathway requires the substrate to be isomerised first.

American English

  • This compound is isomerized by the enzyme.
  • The pathway requires the substrate to be isomerized first.

adverb

British English

  • The reaction proceeded isomerically.
  • The molecule rearranged isomerically.

American English

  • The reaction proceeded isomerically.
  • The molecule rearranged isomerically.

adjective

British English

  • The isomerase activity was measured spectrophotometrically.
  • They identified an isomerase reaction in the cytoplasm.

American English

  • The isomerase activity was measured spectrophotometrically.
  • They identified an isomerase reaction in the cytoplasm.

Examples

By CEFR Level

A2
  • (This word is not used at A2 level.)
B1
  • (This word is not typically used at B1 level.)
B2
  • Enzymes like isomerase are important for chemical changes in cells.
  • The scientist studied an isomerase found in yeast.
C1
  • Topoisomerase is a crucial DNA isomerase that relieves supercoiling during replication.
  • The lack of a specific isomerase can block an entire metabolic pathway, leading to disease.

Learning

Memory Aids

Mnemonic

Think: 'Isomers' are molecules with the same formula but different structures. An 'isomer-ASE' is an enzyme that helps change (makes it happen with ease) one isomer into another.

Conceptual Metaphor

A MACHINE TOOL/RE-ARRANGER: It is conceptualized as a precise biological machine that reconfigures the shape or spatial arrangement of a molecule without changing its parts.

Watch out

Common Pitfalls

Translation Traps (for Russian speakers)

  • Avoid directly translating the '-ase' suffix as '-аза' (-aza) unless certain of the correct Russian biochemical term. The full word 'isomerase' is commonly adopted as 'изомераза'.
  • Do not confuse with 'isomer' (изомер) – the enzyme versus the molecule it acts upon.

Common Mistakes

  • Mispronouncing as 'iso-mer-ase' (stressing 'mer') instead of 'i-SOM-er-ase'.
  • Using it as a general term for any enzyme (it is a very specific subtype).
  • Misspelling as 'isomerease' or 'isomeraze'.

Practice

Quiz

Fill in the gap
A key step in sugar metabolism is catalyzed by the enzyme phosphoglucose .
Multiple Choice

What is the primary function of an isomerase?

FAQ

Frequently Asked Questions

It is the standard suffix used to denote an enzyme. If you see a word ending in '-ase', it is almost certainly an enzyme.

Yes, isomerases are used in various industrial processes, notably in food production (e.g., converting glucose to fructose to make high-fructose corn syrup) and pharmaceutical synthesis.

Mutases are a subclass of isomerases that specifically catalyze the transfer of a functional group (like a phosphate) from one position to another within the same molecule. All mutases are isomerases, but not all isomerases are mutases.

Only in very specific contexts, such as talking about a biochemistry class or a scientific documentary. It is a highly specialized term that would be confusing or out of place in general conversation.