leptin: meaning, definition, pronunciation and examples

C2
UK/ˈlɛptɪn/US/ˈlɛptən/

technical

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Quick answer

What does “leptin” mean?

A protein hormone produced by fat cells that regulates appetite and energy expenditure by signaling satiety to the brain.

Audio

Pronunciation

Definition

Meaning and Definition

A protein hormone produced by fat cells that regulates appetite and energy expenditure by signaling satiety to the brain.

In scientific and medical contexts, leptin is a key adipokine involved in the regulation of body weight, metabolism, and reproductive function. It is often discussed in relation to obesity, leptin resistance, and metabolic syndromes.

Dialectal Variation

British vs American Usage

Differences

None in meaning or usage. Pronunciations differ slightly.

Connotations

Purely scientific/medical in both varieties.

Frequency

Equally low-frequency outside specialist fields in both regions.

Grammar

How to Use “leptin” in a Sentence

Leptin is secreted by adipose tissue.Researchers measured the patient's leptin.Leptin binds to receptors in the hypothalamus.

Vocabulary

Collocations

strong
leptin levelsleptin resistanceleptin receptorserum leptin
medium
produce leptinsecrete leptinleptin deficiencycirculating leptin
weak
high leptinlow leptinleptin functionleptin signalling

Examples

Examples of “leptin” in a Sentence

adjective

British English

  • leptin-resistant patients
  • leptin-mediated signalling

American English

  • leptin-resistant patients
  • leptin-mediated signaling

Usage

Meaning in Context

Academic

Primary usage. Found in endocrinology, physiology, nutrition, and biomedical research journals.

Everyday

Virtually never used in casual conversation.

Technical

Core usage in medical, biochemical, and nutritional science literature and discussions.

Vocabulary

Synonyms of “leptin”

Neutral

satiety hormone

Weak

adipokineadipose hormone

Vocabulary

Antonyms of “leptin”

Watch out

Common Mistakes When Using “leptin”

  • Using 'leptin' to refer to body fat generally.
  • Mispronouncing as /lɛpˈtaɪn/ or /ˈliːptɪn/.

FAQ

Frequently Asked Questions

Leptin signals to your brain that you have enough stored fat, reducing appetite and increasing energy expenditure.

Generally no. Most obese individuals have high leptin levels but are resistant to its effects. Giving more leptin is rarely effective.

From the Greek 'leptos', meaning 'thin'. It was named with the hope it would be a treatment for obesity.

Ghrelin, the 'hunger hormone', which is produced in the stomach and stimulates appetite.

A protein hormone produced by fat cells that regulates appetite and energy expenditure by signaling satiety to the brain.

Leptin is usually technical in register.

Leptin: in British English it is pronounced /ˈlɛptɪn/, and in American English it is pronounced /ˈlɛptən/. Tap the audio buttons above to hear it.

Learning

Memory Aids

Mnemonic

Think: Leptin makes you 'lept' (or stop) eating because you're full. It comes from the Greek 'leptos' meaning thin.

Conceptual Metaphor

LEPTIN IS A MESSENGER / LEPTIN IS A THERMOSTAT FOR BODY FAT.

Practice

Quiz

Fill in the gap
A lack of sensitivity to can lead to overeating and weight gain.
Multiple Choice

Leptin is primarily produced by which type of tissue?