lesion

C1
UK/ˈliːʒ(ə)n/US/ˈliːʒən/

Formal, Academic, Medical

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Definition

Meaning

A region in an organ or tissue which has suffered damage through injury or disease.

Any pathological or traumatic discontinuity of tissue or loss of function of a part. Can be used metaphorically to refer to damage in non-biological systems (e.g., psychological, legal).

Linguistics

Semantic Notes

In medicine, a broad term encompassing wounds, ulcers, abscesses, tumors, and any other visible tissue abnormality. More specific terms (e.g., laceration, tumor) are often used for precision. The verb form is less common.

Dialectal Variation

British vs American Usage

Differences

No significant spelling or meaning differences. In UK medical contexts, 'lesion' may be slightly more formal than 'sore' or 'wound' for superficial damage. US usage heavily dominates in dermatology and neurology literature.

Connotations

Neutral in both variants; strictly clinical/technical.

Frequency

Slightly more frequent in American English due to higher volume of published medical research.

Vocabulary

Collocations

strong
brain lesionskin lesionprimary lesionmalignant lesionbenign lesionidentify a lesionbiopsy the lesion
medium
painful lesionsmall lesionhealing lesioncause a lesiondetect a lesion
weak
serious lesionvisible lesionold lesiontreat the lesionexamine the lesion

Grammar

Valency Patterns

The [noun] caused a lesion [in/on] the [organ].A lesion [was found/was identified] [in/on] the [organ].The patient has a [adjective] lesion.

Vocabulary

Synonyms

Strong

woundsoreulcertumorcyst

Neutral

injurydamageabnormality

Weak

defectdisorderaffliction

Vocabulary

Antonyms

healthy tissueintact areaunblemished skin

Phrases

Idioms & Phrases

  • [No common idioms; used literally]

Usage

Context Usage

Business

Not applicable; used only metaphorically in rare cases (e.g., 'a lesion on the company's reputation').

Academic

Central in medical, biological, and neuroscientific research papers (e.g., 'MRI revealed a focal lesion in the hippocampus.').

Everyday

Rare. If used, it's typically in personal health discussions (e.g., 'The doctor is checking a skin lesion.').

Technical

The primary register. Used in clinical diagnoses, pathology reports, medical imaging, and dermatology.

Examples

By Part of Speech

verb

British English

  • The procedure may lesion the nerve fibres.
  • The virus can lesion the intestinal lining.

American English

  • The surgeon will lesion the targeted brain area.
  • Chemicals can lesion the protective tissue.

adverb

British English

  • [No standard adverbial form]

American English

  • [No standard adverbial form]

adjective

British English

  • [Not standard; 'lesional' is extremely rare in clinical notes.]

American English

  • [Not standard; 'lesional' is extremely rare in clinical notes.]

Examples

By CEFR Level

A2
  • The doctor looked at the red lesion on my arm.
  • She has a small skin lesion.
B1
  • They did a scan to check for any brain lesions.
  • The biopsy showed the lesion was not cancerous.
B2
  • Multiple sclerosis often causes demyelinating lesions visible on an MRI.
  • The primary lesion was surgically removed, but satellite lesions remained.
C1
  • The research focused on the correlation between hippocampal lesions and memory impairment.
  • Precise characterisation of the malignant lesion guided the targeted therapy regimen.

Learning

Memory Aids

Mnemonic

Think: 'LEGION of problems' – a 'lesion' is a spot where a legion of health problems might begin.

Conceptual Metaphor

DAMAGE IS A PHYSICAL OBJECT/LOCATION (e.g., 'a lesion in the brain', 'the lesion site').

Watch out

Common Pitfalls

Translation Traps (for Russian speakers)

  • False friend with Russian 'лезвие' (blade).
  • Not equivalent to 'рана' (wound) in all contexts; 'lesion' is broader and more clinical.
  • In Russian, the direct borrowing 'лезия' is highly technical and rarely used in everyday speech.

Common Mistakes

  • Mispronunciation: /ˈliːzɪən/ instead of /ˈliːʒən/.
  • Using as a verb in non-medical contexts (e.g., 'The scandal lesioned his career' is highly non-standard).
  • Confusing with 'legion'.

Practice

Quiz

Fill in the gap
The MRI scan confirmed the presence of a small in the frontal lobe.
Multiple Choice

In which context is the word 'lesion' MOST appropriately used?

FAQ

Frequently Asked Questions

No, a lesion is simply an area of damaged tissue. It can be benign (non-cancerous), malignant (cancerous), or non-neoplastic (e.g., caused by injury or infection).

Yes, but it is highly technical and almost exclusive to medical/scientific contexts. It means 'to cause a lesion in' or 'to inflict a wound on a specific area'.

A 'wound' typically implies a break in the skin or flesh caused by an external force (trauma). A 'lesion' is a broader medical term for any abnormal tissue change, which can include wounds, but also internal abnormalities, tumors, ulcers, etc., from various causes.

No, it is a specialist term. In everyday conversation, people are more likely to use words like 'sore', 'cut', 'lump', 'rash', or 'wound'. 'Lesion' is used when a precise, clinical term is needed.

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