locked-in syndrome: meaning, definition, pronunciation and examples

Low (Specialized)
UK/ˌlɒkt ˈɪn ˌsɪndrəʊm/US/ˌlɑːkt ˈɪn ˌsɪndroʊm/

Medical/Technical, Figurative (literary/journalistic)

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Quick answer

What does “locked-in syndrome” mean?

A medical condition characterized by complete paralysis of all voluntary muscles except for those controlling eye movement, while cognitive function remains fully intact.

Audio

Pronunciation

Definition

Meaning and Definition

A medical condition characterized by complete paralysis of all voluntary muscles except for those controlling eye movement, while cognitive function remains fully intact.

A metaphorical state of being trapped or unable to act or communicate, despite being mentally aware.

Dialectal Variation

British vs American Usage

Differences

No significant differences in spelling or usage. The term is identical in both varieties.

Connotations

Identical strong medical connotations. The figurative use is equally uncommon in both varieties.

Frequency

Equally low frequency in both, confined to medical/health reporting and specialized discussion.

Grammar

How to Use “locked-in syndrome” in a Sentence

Patient [suffers/has/is diagnosed with] locked-in syndrome.The accident/Stroke resulted in locked-in syndrome.locked-in syndrome [following/after/caused by] a brainstem injury.

Vocabulary

Collocations

strong
diagnosed withsuffer frompatient withcausestate of
medium
classiccompleteincompleteraredevastating
weak
severeterribletotallive withfight

Usage

Meaning in Context

Business

Virtually never used.

Academic

Used in medical, neurological, and bioethics literature.

Everyday

Rare, only in discussions of severe disability or news reports about specific cases.

Technical

Standard term in neurology, neurosurgery, and rehabilitation medicine.

Vocabulary

Synonyms of “locked-in syndrome”

Strong

(none - very specific term)

Neutral

pseudocomade-efferented state (highly technical)

Weak

complete paralysis (descriptive, not a true synonym)

Vocabulary

Antonyms of “locked-in syndrome”

full mobilityunimpaired motor functionmotor freedom

Watch out

Common Mistakes When Using “locked-in syndrome”

  • Misspelling as 'lock-in syndrome' (which suggests an event).
  • Using it loosely for minor immobility.
  • Incorrect hyphenation: 'locked in syndrome'.
  • Capitalization: not typically capitalized unless starting a sentence.

FAQ

Frequently Asked Questions

Yes, cognitive and sensory functions are typically fully intact, meaning they can feel, think, and experience emotions normally.

No, it is entirely different. In a coma, patients are unconscious. In locked-in syndrome, patients are fully conscious and aware.

Pontine hemorrhage or infarction (a type of stroke in the brainstem) is the most frequent cause.

Complete recovery is rare, but some patients may regain limited control over certain movements. Management focuses on communication technology and supportive care.

A medical condition characterized by complete paralysis of all voluntary muscles except for those controlling eye movement, while cognitive function remains fully intact.

Locked-in syndrome is usually medical/technical, figurative (literary/journalistic) in register.

Locked-in syndrome: in British English it is pronounced /ˌlɒkt ˈɪn ˌsɪndrəʊm/, and in American English it is pronounced /ˌlɑːkt ˈɪn ˌsɪndroʊm/. Tap the audio buttons above to hear it.

Phrases

Idioms & Phrases

  • A prisoner in one's own body (common description, not a formal idiom).

Learning

Memory Aids

Mnemonic

Imagine a person fully conscious and aware, but their body is a locked house they cannot leave; only their eyes are windows they can open.

Conceptual Metaphor

THE BODY IS A PRISON / CONSCIOUSNESS IS TRAPPED.

Practice

Quiz

Fill in the gap
After the severe stroke, the patient was diagnosed with , able to communicate only through blinking.
Multiple Choice

What is the primary characteristic of locked-in syndrome?