mannitol: meaning, definition, pronunciation and examples

C2
UK/ˈmænɪtɒl/US/ˈmænɪtɔːl/

Technical / Medical / Chemical

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Quick answer

What does “mannitol” mean?

A sugar alcohol (polyol) used as a sweetener and a medication.

Audio

Pronunciation

Definition

Meaning and Definition

A sugar alcohol (polyol) used as a sweetener and a medication.

A naturally occurring hexitol, an isomer of sorbitol, derived from mannose and found in plants and fungi. It is used industrially as a sweetener in diabetic foods, medically as an osmotic diuretic to reduce intracranial or intraocular pressure, and as a diagnostic agent in kidney function tests.

Dialectal Variation

British vs American Usage

Differences

No significant lexical differences. Pronunciation of the suffix '-itol' may have a slightly softer 't' in some British accents. Both variants use the same spelling.

Connotations

Neutral in both; purely technical/medical term.

Frequency

Equally rare in general language. Frequency is confined to medical, pharmaceutical, food science, and chemistry domains.

Grammar

How to Use “mannitol” in a Sentence

N + for + condition (mannitol for cerebral oedema)N + as + role (mannitol as a sweetener)N + in + formulation (mannitol in the injection)

Vocabulary

Collocations

strong
intravenous mannitolmannitol infusionmannitol saltmannitol solution
medium
administer mannitolcontains mannitolcrystalline mannitoloral mannitol
weak
mannitol therapymannitol powdermannitol testmannitol challenge

Examples

Examples of “mannitol” in a Sentence

verb

British English

  • No verb form.

American English

  • No verb form.

adverb

British English

  • No adverb form.

American English

  • No adverb form.

adjective

British English

  • No standard adjective form. Possible technical derivative: 'mannitol-induced diuresis'.
  • The mannitol-containing solution was prepared.

American English

  • No standard adjective form. Possible technical derivative: 'mannitol-reduced ice cream'.
  • The mannitol-based therapy was effective.

Usage

Meaning in Context

Business

In pharmaceutical or food ingredient supply: 'The contract specifies a shipment of pharmaceutical-grade mannitol.'

Academic

In biochemistry papers: 'The pathway for mannitol biosynthesis was elucidated.'

Everyday

Virtually never used. Possibly on a food label: 'Sweeteners: mannitol, sucralose.'

Technical

In medical instructions: 'Prepare a 20% mannitol solution for IV infusion.'

Vocabulary

Synonyms of “mannitol”

Strong

osmotic diuretic (in medical context)sugar alcohol (in chemical context)

Neutral

D-mannitolOsmitrol (brand name)Mannite

Vocabulary

Antonyms of “mannitol”

hypertonic saline (in specific medical contrast)sucrose (as a different type of sweetener)

Watch out

Common Mistakes When Using “mannitol”

  • Misspelling as 'manitol', 'mannatol'.
  • Incorrect pronunciation stress on the second syllable (/məˈnaɪtəl/).
  • Using it as a countable noun (e.g., 'a mannitol') – it is uncountable.

FAQ

Frequently Asked Questions

It is a naturally occurring substance in many plants and fungi, but it is also produced industrially for commercial use.

Primarily as an osmotic diuretic to reduce high pressure inside the skull (intracranial pressure) or the eye (intraocular pressure).

No. Some people have a hereditary intolerance to mannitol, and excessive consumption can have a laxative effect.

It is a sugar alcohol with fewer calories, a lower glycaemic index, and it does not promote tooth decay. It is not metabolised by oral bacteria.

A sugar alcohol (polyol) used as a sweetener and a medication.

Mannitol is usually technical / medical / chemical in register.

Mannitol: in British English it is pronounced /ˈmænɪtɒl/, and in American English it is pronounced /ˈmænɪtɔːl/. Tap the audio buttons above to hear it.

Phrases

Idioms & Phrases

  • No idioms.

Learning

Memory Aids

Mnemonic

MANniTOL: Think of a MAN giving a sweet TOLL (payment) – a man-made sweetener used as a medicinal payment/treatment.

Conceptual Metaphor

MANNITOL IS A TOOL (for reducing pressure or for sweetening).

Practice

Quiz

Fill in the gap
The patient with acute intracranial hypertension received an immediate infusion.
Multiple Choice

In which of the following contexts is 'mannitol' most likely to be used?