mefloquine: meaning, definition, pronunciation and examples

Low
UK/ˈmɛflə(ʊ)kwiːn/US/ˈmɛfloʊˌkwin/

Technical/Medical

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Quick answer

What does “mefloquine” mean?

A synthetic drug used to prevent and treat malaria.

Audio

Pronunciation

Definition

Meaning and Definition

A synthetic drug used to prevent and treat malaria.

A quinoline-derivative antimalarial medication known for its effectiveness against chloroquine-resistant strains of malaria, but also associated with significant neuropsychiatric side effects.

Dialectal Variation

British vs American Usage

Differences

No significant lexical or grammatical differences. The drug is known by the same International Nonproprietary Name (INN).

Connotations

In both varieties, it carries strong connotations of malaria prophylaxis and serious potential side effects.

Frequency

Slightly higher frequency in British English due to historical use in Commonwealth travel medicine guidelines, but the term is equally specialized in both varieties.

Grammar

How to Use “mefloquine” in a Sentence

Patients are advised to take [mefloquine] once weekly.The doctor prescribed [mefloquine] for malaria prevention.[Mefloquine] is contraindicated in patients with a history of psychiatric disorders.

Vocabulary

Collocations

strong
take mefloquinemefloquine prophylaxismefloquine resistancemefloquine hydrochloride
medium
prescribe mefloquineside effects of mefloquinedose of mefloquinestop taking mefloquine
weak
mefloquine tabletmefloquine therapymefloquine usermefloquine and chloroquine

Examples

Examples of “mefloquine” in a Sentence

adjective

British English

  • The mefloquine regimen must be started three weeks before travel.

American English

  • She experienced a mefloquine-related adverse event.

Usage

Meaning in Context

Business

Rare, except in pharmaceutical industry reports or travel insurance documents.

Academic

Common in medical, pharmacological, and tropical medicine literature.

Everyday

Very rare; used only by travelers receiving medical advice or individuals discussing specific medication experiences.

Technical

Standard term in medical, pharmacological, and public health contexts concerning malaria treatment and prevention.

Vocabulary

Synonyms of “mefloquine”

Neutral

Lariam (brand name)

Weak

antimalarialmalaria prophylactic

Watch out

Common Mistakes When Using “mefloquine”

  • Misspelling as 'mefloquin' (dropping the 'e'), 'mefloquene', or 'mefloqine'.
  • Using it as a countable noun in plural without 'tablets' (e.g., 'I took two mefloquines' is non-standard; prefer 'two mefloquine tablets').

FAQ

Frequently Asked Questions

Yes, Lariam is a common brand name for the drug whose generic name is mefloquine.

For prevention, it is usually taken once a week, starting 2-3 weeks before travel, during travel, and for 4 weeks after leaving the malarious area.

It is associated with potentially severe and long-lasting neuropsychiatric side effects, including anxiety, paranoia, depression, and vivid nightmares, which have led to restrictions in its use.

No. It is contraindicated for people with a history of psychiatric disorders, seizures, or certain heart conditions. A doctor must assess individual suitability.

A synthetic drug used to prevent and treat malaria.

Mefloquine is usually technical/medical in register.

Mefloquine: in British English it is pronounced /ˈmɛflə(ʊ)kwiːn/, and in American English it is pronounced /ˈmɛfloʊˌkwin/. Tap the audio buttons above to hear it.

Learning

Memory Aids

Mnemonic

Think: 'ME'dicine for 'FLO'wing to regions with ma'QUINE' (a play on 'canine' for bite) from mosquitos. MEFLO-QUINE.

Conceptual Metaphor

A SHIELD/GUARD (against the invasion of malaria parasites).

Practice

Quiz

Fill in the gap
Travelers to regions with chloroquine-resistant malaria are often advised to consider as a prophylactic option.
Multiple Choice

What is a major clinical concern associated with mefloquine?

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