megacephaly: meaning, definition, pronunciation and examples

C2/Technical
UK/ˌmɛɡəˈsɛfəli/US/ˌmɛɡəˈsɛfəli/

Formal, Medical/Scientific

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Quick answer

What does “megacephaly” mean?

a medical condition characterized by an abnormally large head.

Audio

Pronunciation

Definition

Meaning and Definition

a medical condition characterized by an abnormally large head

While strictly medical, it can metaphorically describe anything disproportionately large-headed or conceptually 'big-headed' in non-literal contexts

Dialectal Variation

British vs American Usage

Differences

No significant difference in meaning. 'Macrocephaly' is a more common synonym in both varieties.

Connotations

Purely clinical and neutral in both varieties.

Frequency

Extremely rare in general discourse; confined to medical literature, case reports, and specialized discussions.

Grammar

How to Use “megacephaly” in a Sentence

The infant presented with + [megacephaly][Megacephaly] + is often associated with + [syndrome/disorder][Diagnosis/tests] + revealed + [megacephaly]

Vocabulary

Collocations

strong
congenital megacephalydiagnosed with megacephalysymptomatic megacephalyfamilial megacephalyprogressive megacephaly
medium
causes of megacephalyassociated with megacephalypresenting with megacephalymegacephaly and developmental delay
weak
severe megacephalymild megacephalyinfant megacephalyproblem of megacephaly

Examples

Examples of “megacephaly” in a Sentence

adjective

British English

  • The megacephalic skull showed distinctive frontal bossing on the radiograph.

American English

  • The megacephalic infant was referred for genetic counseling.

Usage

Meaning in Context

Business

Virtually never used.

Academic

Used in medical, biological, and genetic research papers.

Everyday

Extremely rare; would only be used by a professional explaining a diagnosis to a patient/family.

Technical

The primary context of use; found in clinical neurology, pediatrics, radiology reports, and genetics.

Vocabulary

Synonyms of “megacephaly”

Neutral

macrocephalylarge head circumference

Weak

cranial enlargementincreased head size

Vocabulary

Antonyms of “megacephaly”

Watch out

Common Mistakes When Using “megacephaly”

  • Using it to describe a healthy person with a naturally large head (incorrect – implies a medical abnormality).
  • Spelling: 'megacephaly' vs. 'megacephalie' (French-influenced).
  • Confusing it with 'hydrocephaly' (specifically due to fluid).

FAQ

Frequently Asked Questions

No. Hydrocephalus is a specific cause of megacephaly involving cerebrospinal fluid accumulation. Megacephaly is a broader term for a large head from any cause (e.g., thickened bones, brain overgrowth).

Almost never. It is a highly technical medical term. Using it metaphorically (e.g., 'the company's megacephaly') would be very obscure and stylistically jarring.

They are often used interchangeably in medicine. Some specialists use 'macrocephaly' for head circumference >2 standard deviations above the mean, and 'megacephaly' for more extreme cases, but this distinction is not consistent.

It is a noun. The related adjective is 'megacephalic'.

a medical condition characterized by an abnormally large head.

Megacephaly is usually formal, medical/scientific in register.

Megacephaly: in British English it is pronounced /ˌmɛɡəˈsɛfəli/, and in American English it is pronounced /ˌmɛɡəˈsɛfəli/. Tap the audio buttons above to hear it.

Learning

Memory Aids

Mnemonic

Think: MEGA (very large) + CEPHALY (relating to the head, from Greek 'kephalē') = very large head condition.

Conceptual Metaphor

HEAD SIZE IS VOLUME/CAPACITY (pathologically increased).

Practice

Quiz

Fill in the gap
The neuroimaging confirmed the diagnosis of , explaining the infant's rapidly increasing head circumference.
Multiple Choice

Which of the following is the most precise clinical synonym for 'megacephaly'?

megacephaly: meaning, definition, pronunciation and examples | Lingvocore