megakaryoblast: meaning, definition, pronunciation and examples
Very LowTechnical/Medical
Quick answer
What does “megakaryoblast” mean?
The earliest, immature precursor cell in the bone marrow that develops into a megakaryocyte, which produces blood platelets.
Audio
Pronunciation
Definition
Meaning and Definition
The earliest, immature precursor cell in the bone marrow that develops into a megakaryocyte, which produces blood platelets.
In pathology, an abnormally proliferating cell characteristic of a specific subtype of acute myeloid leukemia (AML M7).
Dialectal Variation
British vs American Usage
Differences
No differences in meaning, spelling, or usage. Pronunciations may have minor phonetic variations.
Connotations
None beyond its precise medical definition.
Frequency
Extremely rare in both varieties, used identically in specialist contexts.
Grammar
How to Use “megakaryoblast” in a Sentence
[The] megakaryoblast [of/from/in] the bone marrow[A] proliferation of megakaryoblastsVocabulary
Collocations
Usage
Meaning in Context
Academic
Used in medical research papers, haematology textbooks, and oncology studies.
Everyday
Virtually never used in everyday conversation.
Technical
Used in clinical diagnoses, bone marrow biopsy reports, and specialist medical discussions.
Vocabulary
Synonyms of “megakaryoblast”
Neutral
Weak
Vocabulary
Antonyms of “megakaryoblast”
Watch out
Common Mistakes When Using “megakaryoblast”
- Mispronouncing with stress on the first syllable (ME-ga...).
- Misspelling as 'megacaryoblast', 'megakaryablast', or 'megakaryblasto'.
FAQ
Frequently Asked Questions
Acute megakaryoblastic leukemia (AML M7), a subtype of acute myeloid leukemia.
No, it is a precursor cell in the platelet (thrombocyte) lineage, not the white blood cell (leukocyte) lineage.
No, they are normally found only in the bone marrow and do not circulate in peripheral blood under healthy conditions.
From Greek: 'mega-' (large), 'karyon' (nut, kernel, nucleus), and '-blast' (germ, bud, immature cell).
The earliest, immature precursor cell in the bone marrow that develops into a megakaryocyte, which produces blood platelets.
Megakaryoblast is usually technical/medical in register.
Megakaryoblast: in British English it is pronounced /ˌmɛɡəˈkærɪə(ʊ)blɑːst/, and in American English it is pronounced /ˌmɛɡəˈkɛriəˌblæst/. Tap the audio buttons above to hear it.
Learning
Memory Aids
Mnemonic
Think: MEGA (large) + KARYO (nucleus) + BLAST (immature cell) = a large-nucleated immature cell that becomes a platelet factory.
Practice
Quiz
What is the primary function of the mature cell derived from a megakaryoblast?