mercapto group: meaning, definition, pronunciation and examples

C2/Technical
UK/mɜːˈkæptəʊ ɡruːp/US/mɝˈkæptoʊ ɡrup/

Formal, scientific/technical.

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Quick answer

What does “mercapto group” mean?

A functional group in organic chemistry consisting of a sulfur atom bonded to a hydrogen atom (-SH).

Audio

Pronunciation

Definition

Meaning and Definition

A functional group in organic chemistry consisting of a sulfur atom bonded to a hydrogen atom (-SH); equivalent to a thiol group.

A reactive chemical moiety containing sulfur and hydrogen, crucial in biochemistry (e.g., in cysteine amino acids), coordination chemistry as a ligand, and industrial processes like vulcanization.

Dialectal Variation

British vs American Usage

Differences

No significant lexical or spelling differences. Usage is identical in scientific literature.

Connotations

None beyond its strict technical meaning.

Frequency

Identically low frequency, confined to chemistry, biochemistry, and related technical fields.

Grammar

How to Use “mercapto group” in a Sentence

The [compound] possesses a mercapto group.The reaction targets the [molecule]'s mercapto group.A [polymer] with pendant mercapto groups was synthesized.

Vocabulary

Collocations

strong
contains a mercapto groupmercapto group terminationmercapto group functionalized
medium
reactive mercapto groupterminal mercapto groupfree mercapto group
weak
important mercapto groupchemical mercapto groupspecific mercapto group

Examples

Examples of “mercapto group” in a Sentence

verb

British English

  • The compound was functionalised to mercapto-terminate the polymer chain.
  • The agent will mercapto-coat the surface.

American English

  • The compound was functionalized to mercapto-terminate the polymer chain.
  • The agent will mercapto-coat the surface.

adverb

British English

  • N/A (Not used adverbially).

American English

  • N/A (Not used adverbially).

adjective

British English

  • The mercapto-functionalised silica showed high adsorption.
  • We analysed the mercapto-containing derivative.

American English

  • The mercapto-functionalized silica showed high adsorption.
  • We analyzed the mercapto-containing derivative.

Usage

Meaning in Context

Business

Virtually never used outside businesses dealing with specialty chemicals or pharmaceuticals.

Academic

Used in chemistry, biochemistry, materials science, and pharmacology research papers and textbooks.

Everyday

Not used in everyday conversation.

Technical

Core term in organic synthesis, polymer chemistry, biochemistry (e.g., describing cysteine residues), and toxicology (e.g., binding of heavy metals).

Vocabulary

Synonyms of “mercapto group”

Strong

-SH group

Neutral

thiol groupsulfhydryl group

Weak

sulfur-hydrogen group

Vocabulary

Antonyms of “mercapto group”

hydroxyl group (-OH)alkoxy group

Watch out

Common Mistakes When Using “mercapto group”

  • Pronouncing it as /ˈmɜːrkəptoʊ/. Correct stress is on the second syllable: mer-CAP-to.
  • Confusing it with a 'methyl group' due to similar sound beginnings.
  • Using 'mercaptan group' incorrectly; 'mercaptan' refers to the whole thiol molecule, not just the -SH substituent.

FAQ

Frequently Asked Questions

Essentially yes, but the usage differs slightly. 'Thiol' (R-SH) refers to the whole molecule, while 'mercapto group' specifically refers to the -SH functional group when it is a substituent part of a larger molecule, often indicated by the prefix 'mercapto-' in chemical names.

The name derives from the Latin 'mercurium captans,' meaning 'capturing mercury,' because these groups form strong bonds with mercury(II) ions.

They are key in the vulcanization of rubber, in the synthesis of certain pharmaceuticals, and as odorants in natural gas (where trace thiols like ethyl mercaptan are added for leak detection due to their strong smell).

It is weakly acidic. The S-H bond can dissociate to a small extent, releasing a proton (H+), forming a thiolate anion (S-). This property is vital in many biochemical redox reactions.

A functional group in organic chemistry consisting of a sulfur atom bonded to a hydrogen atom (-SH).

Mercapto group is usually formal, scientific/technical. in register.

Mercapto group: in British English it is pronounced /mɜːˈkæptəʊ ɡruːp/, and in American English it is pronounced /mɝˈkæptoʊ ɡrup/. Tap the audio buttons above to hear it.

Phrases

Idioms & Phrases

  • N/A (Technical term)

Learning

Memory Aids

Mnemonic

Think of MERCury APT to grab it: the 'mercapto' group is historically known for capturing (binding) mercury atoms.

Conceptual Metaphor

A chemical 'hook' or 'handle' (due to its reactivity and ability to form bonds with metals and other groups).

Practice

Quiz

Fill in the gap
The strong odour of many thiols is due to the volatile nature of the .
Multiple Choice

What is the primary chemical composition of a mercapto group?