mercaptopurine: meaning, definition, pronunciation and examples
Very LowTechnical/Scientific
Quick answer
What does “mercaptopurine” mean?
A medication used to treat certain types of cancer, specifically acute lymphocytic leukemia.
Audio
Pronunciation
Definition
Meaning and Definition
A medication used to treat certain types of cancer, specifically acute lymphocytic leukemia.
An antimetabolite chemotherapeutic agent (thiopurine) that interferes with DNA and RNA synthesis in cancer cells. It is also used in immunosuppressive therapy for inflammatory bowel disease.
Dialectal Variation
British vs American Usage
Differences
No significant lexical differences. The drug is known by the same International Nonproprietary Name (INN).
Connotations
Identical clinical and pharmacological connotations in both varieties.
Frequency
Equally rare and specialized outside medical contexts in both the UK and US.
Grammar
How to Use “mercaptopurine” in a Sentence
[Patient] is prescribed mercaptopurine for [condition][Dosage] of mercaptopurine is administered [route]Mercaptopurine is used to treat/manage [disease]Vocabulary
Collocations
Examples
Examples of “mercaptopurine” in a Sentence
adjective
British English
- The mercaptopurine regimen was started yesterday.
- We reviewed the mercaptopurine dosage guidelines.
American English
- The mercaptopurine protocol has been updated.
- We need a mercaptopurine level test.
Usage
Meaning in Context
Business
Not used.
Academic
Used in medical and pharmacological research papers and textbooks.
Everyday
Virtually never used in general conversation.
Technical
Exclusively used in clinical medicine, oncology, pharmacy, and biomedical sciences.
Vocabulary
Synonyms of “mercaptopurine”
Vocabulary
Antonyms of “mercaptopurine”
Watch out
Common Mistakes When Using “mercaptopurine”
- Misspelling as 'mercaptapurine' or 'mercaptipurine'.
- Mispronouncing 'purine' as /'pjʊəraɪn/ instead of /'pjʊəriːn/.
FAQ
Frequently Asked Questions
Yes, it is a type of chemotherapy drug known as an antimetabolite.
It is typically taken orally in tablet form.
Yes, it is also used as an immunosuppressant for autoimmune conditions like inflammatory bowel disease.
Common side effects can include nausea, loss of appetite, bone marrow suppression (leading to low blood counts), and increased risk of infection.
A medication used to treat certain types of cancer, specifically acute lymphocytic leukemia.
Mercaptopurine is usually technical/scientific in register.
Mercaptopurine: in British English it is pronounced /mɜːˌkæptəʊˈpjʊəriːn/, and in American English it is pronounced /mɚˌkæptoʊˈpjʊrin/. Tap the audio buttons above to hear it.
Learning
Memory Aids
Mnemonic
Think: MERCy for the patient + CAPTured + PURINE (the target in cells). A drug showing mercy by capturing/countering purine in cancer cells.
Conceptual Metaphor
CELLULAR SABOTEUR / METABOLIC MIMIC (it mimics a natural cellular component to disrupt cancer cell function).
Practice
Quiz
What is the primary clinical use of mercaptopurine?