methadone: meaning, definition, pronunciation and examples

C1/C2
UK/ˈmeθ.ə.dəʊn/US/ˈmeθ.ə.doʊn/

Medical, clinical, public health, journalistic.

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Quick answer

What does “methadone” mean?

A synthetic opioid medication used to treat opioid use disorder, particularly addiction to heroin.

Audio

Pronunciation

Definition

Meaning and Definition

A synthetic opioid medication used to treat opioid use disorder, particularly addiction to heroin.

A long-acting opioid agonist used medically for pain management and as a replacement therapy in opioid addiction treatment programmes.

Dialectal Variation

British vs American Usage

Differences

No significant lexical differences. Both use 'methadone clinic' and 'methadone maintenance'. Spelling is identical.

Connotations

Similar negative societal connotations in both varieties, associated with urban drug problems.

Frequency

Frequency is comparable, appearing in medical, policy, and news contexts.

Grammar

How to Use “methadone” in a Sentence

be prescribed methadonebe on methadonereceive methadone treatmentadminister methadone

Vocabulary

Collocations

strong
methadone clinicmethadone maintenancemethadone treatmentprescribe methadonemethadone dose
medium
on methadonemethadone programmemethadone therapyliquid methadone
weak
methadone usermethadone addictioncommunity methadone

Examples

Examples of “methadone” in a Sentence

verb

British English

  • [Rare as a verb]

American English

  • [Rare as a verb]

adverb

British English

  • [No adverbial form]

American English

  • [No adverbial form]

adjective

British English

  • [Rare as a pure adjective; used in compounds like 'methadone-related deaths']

American English

  • [Rare as a pure adjective; used in compounds like 'methadone-funded clinic']

Usage

Meaning in Context

Business

Rare, except in pharmaceuticals or healthcare administration.

Academic

Common in medical, pharmacological, public health, and social policy research.

Everyday

Used in general discussion of drug addiction and treatment, often with negative overtones.

Technical

Core term in addiction medicine and pain management.

Vocabulary

Synonyms of “methadone”

Strong

Dolophine (brand name)

Neutral

opioid agonist therapypharmacotherapy

Weak

synthetic opioidreplacement therapy

Vocabulary

Antonyms of “methadone”

Watch out

Common Mistakes When Using “methadone”

  • Misspelling as 'methadonne' or 'methadon'.
  • Using as a general term for any addiction treatment.
  • Confusing it with buprenorphine or other opioid treatments.

FAQ

Frequently Asked Questions

Yes, methadone is itself an addictive opioid, but its long-acting nature and controlled administration in medical settings make it a safer alternative to street opioids like heroin, used to stabilise patients and reduce harmful behaviours.

Both are used in medication-assisted treatment. Methadone is a full opioid agonist, while buprenorphine is a partial agonist, which means it has a lower risk of overdose but may be less effective for some patients with severe addictions.

If misused, especially by those without opioid tolerance, methadone can produce euphoria and is dangerous. In a controlled clinical dose for a tolerant patient, it prevents withdrawal without causing a significant 'high'.

Controversy stems from the view that it perpetuates addiction rather than promoting complete abstinence. There are also concerns about diversion to the illicit market and the social impact of methadone clinics in communities.

A synthetic opioid medication used to treat opioid use disorder, particularly addiction to heroin.

Methadone is usually medical, clinical, public health, journalistic. in register.

Methadone: in British English it is pronounced /ˈmeθ.ə.dəʊn/, and in American English it is pronounced /ˈmeθ.ə.doʊn/. Tap the audio buttons above to hear it.

Phrases

Idioms & Phrases

  • [No common idioms for this specific term]

Learning

Memory Aids

Mnemonic

METH-Adone: Think of it as a medical method to be 'done' with heroin addiction.

Conceptual Metaphor

ADDICTION IS A DISEASE / TREATMENT IS A SUBSTITUTE (a 'crutch' or 'replacement').

Practice

Quiz

Fill in the gap
Patients in the addiction programme receive a daily dose at the clinic.
Multiple Choice

Methadone is primarily used to treat addiction to which substance?

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