methyl transferase: meaning, definition, pronunciation and examples

Low (highly technical)
UK/ˌmɛθɪl ˈtrænsfəreɪz/US/ˌmɛθɪl ˈtrænsfəreɪs/

Academic / Scientific / Technical

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Quick answer

What does “methyl transferase” mean?

An enzyme that catalyzes the transfer of a methyl group from one molecule to another.

Audio

Pronunciation

Definition

Meaning and Definition

An enzyme that catalyzes the transfer of a methyl group from one molecule to another.

A class of enzymes involved in a crucial biochemical modification process (methylation), essential for gene regulation, protein function, and metabolism.

Dialectal Variation

British vs American Usage

Differences

No significant lexical differences. Spelling conventions follow standard patterns (e.g., 'catalyse' vs. 'catalyze' in surrounding text).

Connotations

Identical technical connotations in both varieties.

Frequency

Equally low-frequency and specialized in both UK and US academic and research contexts.

Grammar

How to Use “methyl transferase” in a Sentence

[Substrate] methyl transferasemethyl transferase that [verb phrase]methyl transferase activity in [location]inhibition of methyl transferase

Vocabulary

Collocations

strong
DNA methyl transferasehistone methyl transferasecatechol-O-methyl transferaseinhibit methyl transferasemethyl transferase activitymethyl transferase enzyme
medium
specific methyl transferasehuman methyl transferasebacterial methyl transferasefunction of methyl transferase
weak
study the methyl transferaserole of methyl transferaseimportant methyl transferase

Examples

Examples of “methyl transferase” in a Sentence

verb

British English

  • The enzyme catalyses the transfer of a methyl group.

American English

  • The enzyme catalyzes the transfer of a methyl group.

adjective

British English

  • The methyl transferase activity was measured.
  • She studied the methyl-transferase pathway.

American English

  • The methyltransferase activity was measured.
  • She studied the methyltransferase pathway.

Usage

Meaning in Context

Business

Rare, except in biotech/pharma investment reports discussing drug targets (e.g., 'The compound is a potent methyl transferase inhibitor').

Academic

Common in biochemistry, molecular biology, genetics, pharmacology, and medical research papers.

Everyday

Virtually never used.

Technical

Core terminology in laboratory protocols, scientific discussions, and technical specifications.

Vocabulary

Synonyms of “methyl transferase”

Neutral

methyltransferasemethylating enzyme

Weak

methylation enzyme

Vocabulary

Antonyms of “methyl transferase”

demethylasemethyl esterase

Watch out

Common Mistakes When Using “methyl transferase”

  • Misspelling as 'methyltransferase' (often accepted as one word) or 'methyl transferace'.
  • Incorrect plural: 'methyl transferases'.
  • Using it as a verb (e.g., 'The protein methyl transferases the histone' - incorrect; use 'methylates').

FAQ

Frequently Asked Questions

In many modern biochemical texts and databases, it is often written as a single word: 'methyltransferase'. Both forms are understood.

'Methylase' is a broader, less specific term for any enzyme that catalyses methylation. 'Methyl transferase' is more precise, explicitly indicating the transfer mechanism.

They are key drug targets, especially in cancer and neurology, because abnormal methylation patterns (caused by dysregulated methyl transferases) are linked to many diseases.

No, it is strictly a noun. The related verb is 'methylate' (e.g., 'The enzyme methylates the substrate').

An enzyme that catalyzes the transfer of a methyl group from one molecule to another.

Methyl transferase is usually academic / scientific / technical in register.

Methyl transferase: in British English it is pronounced /ˌmɛθɪl ˈtrænsfəreɪz/, and in American English it is pronounced /ˌmɛθɪl ˈtrænsfəreɪs/. Tap the audio buttons above to hear it.

Learning

Memory Aids

Mnemonic

Think: 'METHYL' is the GROUP being moved, and 'TRANSFERASE' is the enzyme that TRANSFERS it. It's a 'group mover' for methylation.

Conceptual Metaphor

A molecular postman (delivering a methyl package) / A biochemical switch operator (adding a methyl tag to turn processes on/off).

Practice

Quiz

Fill in the gap
The enzyme known as a is responsible for adding methyl groups to DNA.
Multiple Choice

What is the primary function of a methyl transferase?