metolazone: meaning, definition, pronunciation and examples

Low (Specialist/Technical)
UK/mɪˈtɒləzəʊn/US/məˈtɑːləzoʊn/

Technical/Medical

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Quick answer

What does “metolazone” mean?

A thiazide-like diuretic medication used to treat hypertension (high blood pressure) and edema caused by heart failure, liver disease, or kidney disorders.

Audio

Pronunciation

Definition

Meaning and Definition

A thiazide-like diuretic medication used to treat hypertension (high blood pressure) and edema caused by heart failure, liver disease, or kidney disorders.

A pharmaceutical compound that inhibits sodium reabsorption in the distal convoluted tubule of the nephron, promoting water excretion while preserving potassium levels more effectively than some other diuretics.

Dialectal Variation

British vs American Usage

Differences

No significant differences in meaning or use. Spelling and pronunciation are identical.

Connotations

None beyond its medical function.

Frequency

Equally low frequency in both dialects, confined strictly to medical contexts.

Grammar

How to Use “metolazone” in a Sentence

The doctor prescribed [metolazone] for the edema.The patient takes [metolazone] daily.[Metolazone] is effective in treating fluid retention.

Vocabulary

Collocations

strong
prescribe metolazonetake metolazonemetolazone therapydose of metolazone
medium
respond to metolazonemetolazone treatmentdiscontinue metolazonemetolazone tablets
weak
monitor on metolazoneeffects of metolazonemetolazone and hypertensionpatient on metolazone

Examples

Examples of “metolazone” in a Sentence

verb

British English

  • The doctor may decide to metolazone the patient if other diuretics fail. (Note: Extremely rare/innovative usage)

American English

  • The protocol suggests metolazoning the patient before the procedure. (Note: Extremely rare/innovative usage)

adverb

British English

  • The fluid was removed metolazone-efficiently. (Note: Highly contrived)

American English

  • He responded metolazone-quickly to the therapy. (Note: Highly contrived)

adjective

British English

  • The metolazone dose was carefully titrated.
  • She experienced a metolazone-induced diuresis.

American English

  • The patient's metolazone regimen was adjusted.
  • A metolazone-specific side effect was noted.

Usage

Meaning in Context

Business

Not used.

Academic

Used in pharmacology, medicine, and clinical research papers discussing diuretic therapy.

Everyday

Virtually never used in everyday conversation outside of a patient discussing their specific medication.

Technical

The primary context. Used in medical diagnosis, treatment plans, prescription, and pharmacology literature.

Vocabulary

Synonyms of “metolazone”

Strong

thiazide-like diureticquinazoline diuretic

Neutral

Zaroxolyn (brand name)

Weak

water pill (lay term for diuretics in general)

Vocabulary

Antonyms of “metolazone”

antidiureticfluid-retaining agent

Watch out

Common Mistakes When Using “metolazone”

  • Misspelling as 'metalazone', 'metolozone', or 'metholazone'.
  • Incorrectly classifying it as a typical thiazide diuretic instead of 'thiazide-like'.
  • Using it as a common noun (e.g., 'a metolazone') instead of an uncountable proper drug name.

FAQ

Frequently Asked Questions

It is used to treat high blood pressure and swelling (edema) caused by conditions like heart failure, kidney disease, or liver cirrhosis.

No, they are different types of diuretics. Furosemide is a loop diuretic, while metolazone is a thiazide-like diuretic. They work on different parts of the kidney and are sometimes used together for a stronger effect.

Common side effects can include dizziness, lightheadedness, headache, or upset stomach. Like all diuretics, it can cause electrolyte imbalances, so monitoring is important.

No. You should never stop taking prescription medication without consulting your doctor. Suddenly stopping can cause your blood pressure to rise or fluid to accumulate again.

A thiazide-like diuretic medication used to treat hypertension (high blood pressure) and edema caused by heart failure, liver disease, or kidney disorders.

Metolazone is usually technical/medical in register.

Metolazone: in British English it is pronounced /mɪˈtɒləzəʊn/, and in American English it is pronounced /məˈtɑːləzoʊn/. Tap the audio buttons above to hear it.

Phrases

Idioms & Phrases

  • None

Learning

Memory Aids

Mnemonic

Think: 'MET' (like a goal in medicine to reduce fluid) + 'OL' (sounds like 'all') + 'AZONE' (like a treatment zone). Helps remember it's a medication for removing all excess fluid from the body's zones (tissues).

Conceptual Metaphor

A fluid-draining agent / A release valve for bodily pressure.

Practice

Quiz

Fill in the gap
For patients with resistant edema, clinicians may add to a loop diuretic regimen to achieve adequate diuresis.
Multiple Choice

Metolazone is primarily classified as what type of agent?

metolazone: meaning, definition, pronunciation and examples | Lingvocore