molecule

C1
UK/ˈmɒl.ɪ.kjuːl/US/ˈmɑː.lɪ.kjuːl/

Formal, Academic, Technical

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Definition

Meaning

The smallest physical unit of a chemical element or compound, consisting of two or more atoms held together by chemical bonds.

A minute particle; a tiny amount of something; used metaphorically to describe the smallest component of a complex entity or system.

Linguistics

Semantic Notes

The primary sense is overwhelmingly scientific. The metaphorical use is possible but less common and typically self-conscious or literary. It is a countable noun.

Dialectal Variation

British vs American Usage

Differences

No significant differences in meaning or usage. Pronunciation differs slightly (see IPA). Spelling and grammar are identical.

Connotations

Identical, strongly linked to chemistry and physical sciences.

Frequency

Equally frequent in scientific contexts in both varieties. Non-scientific metaphorical use is rare in both.

Vocabulary

Collocations

strong
water moleculeorganic moleculediatomic moleculecomplex moleculesingle moleculemolecule of waterstructure of a moleculesize of a moleculeshape of a molecule
medium
protein moleculeDNA moleculesimple moleculepolar moleculesymmetrical moleculedetect a moleculeform a moleculebind to a molecule
weak
giant moleculetarget moleculeindividual moleculeparticular moleculespecific moleculeanalyse a moleculestudy a moleculeidentify a molecule

Grammar

Valency Patterns

molecule of [substance]molecule consisting of [atoms]molecule that/which [clause]

Vocabulary

Synonyms

Strong

compound (in some contexts)chemical species

Neutral

particleunit

Weak

speckiotafragment (metaphorical)

Vocabulary

Antonyms

macroscopic objectbulk materialaggregatemass

Phrases

Idioms & Phrases

  • Not a molecule of truth (in it): meaning not even the smallest amount of truth.

Usage

Context Usage

Business

Virtually unused, except in specific industries like pharmaceuticals or materials science (e.g., 'We patented the new molecule').

Academic

Extremely common in chemistry, biochemistry, physics, and materials science papers and textbooks.

Everyday

Rare, mainly in simplified explanations of science (e.g., 'A water molecule has two hydrogen atoms').

Technical

The primary, precise term in all fields of chemistry and molecular biology.

Examples

By Part of Speech

adjective

British English

  • The molecular structure was analysed.
  • They studied molecular biology.

American English

  • The molecular structure was analyzed.
  • They studied molecular biology.

Examples

By CEFR Level

A2
  • Water is made of tiny molecules.
B1
  • A molecule of oxygen gas contains two atoms.
  • Scientists can see single molecules with special microscopes.
B2
  • The drug's effectiveness depends on the precise shape of its molecule.
  • In this reaction, one large molecule splits into two smaller ones.
C1
  • The researcher elucidated the molecule's conformational dynamics using NMR spectroscopy.
  • Supramolecular chemistry deals with structures composed of multiple molecules held together by non-covalent bonds.

Learning

Memory Aids

Mnemonic

Think of a MOLE (the small animal) in a CUE ball (a pool ball). A tiny 'mole' is the core of the 'cue ball' structure.

Conceptual Metaphor

BUILDING BLOCK / SMALLEST UNIT: Conceptualized as the fundamental, indivisible (in a practical sense) component from which larger structures are built.

Watch out

Common Pitfalls

Translation Traps (for Russian speakers)

  • The Russian word 'молекула' is a direct cognate with identical meaning and usage. No trap exists.

Common Mistakes

  • Using 'atom' and 'molecule' interchangeably (an atom is a single element; a molecule is a group of atoms).
  • Pronouncing it as /moʊˈliːkjuːl/ (incorrect stress).
  • Using plural verb forms with 'molecule' as a collective noun (e.g., 'The molecule are...' is wrong).

Practice

Quiz

Fill in the gap
A water consists of two hydrogen atoms and one oxygen atom.
Multiple Choice

Which of the following best describes a molecule?

FAQ

Frequently Asked Questions

An atom is the smallest unit of a chemical element (e.g., one iron atom). A molecule is a group of two or more atoms held together by chemical bonds (e.g., O2, H2O, CH4).

No, by definition a molecule requires at least two atoms. Noble gases like helium or argon exist as single atoms, not molecules, in their natural state.

Rarely. It is sometimes used metaphorically to mean 'a tiny amount' (e.g., 'There wasn't a molecule of evidence'), but this is stylised and not common in everyday speech.

The stress is on the first syllable: MOL-e-cule. The common mispronunciation 'mo-LE-cule' (stress on the second syllable) is incorrect.

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B1 · 47 words · Basic scientific concepts and modern technology.

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