monoamine: meaning, definition, pronunciation and examples

C1/C2
UK/ˌmɒnəʊəˈmiːn/US/ˌmɑːnoʊəˈmiːn/

Technical/Scientific (Biochemistry, Neurology, Pharmacology, Psychiatry)

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Quick answer

What does “monoamine” mean?

A compound (e.

Audio

Pronunciation

Definition

Meaning and Definition

A compound (e.g., a neurotransmitter) containing a single amino group (-NH2) connected to an aromatic ring.

Any of a class of biologically important compounds derived from aromatic amino acids, such as serotonin, dopamine, and norepinephrine, which function primarily as neurotransmitters in the brain and nervous system.

Dialectal Variation

British vs American Usage

Differences

No significant spelling or usage differences. The term is used identically in scientific contexts. Potential minor variation in the colloquial pronunciation of the 'o' in 'mono-'.

Connotations

Identical technical connotations.

Frequency

Equally low-frequency in general language, but standard and common in specialised scientific and medical fields in both regions.

Grammar

How to Use “monoamine” in a Sentence

[determiner] + monoamine + [of/in] + [noun phrase] (e.g., the monoamine serotonin)[adjective] + monoamine + [noun] (e.g., key monoamine neurotransmitters)to affect/inhibit/alter/modulate + monoamine + [levels/activity/reuptake]

Vocabulary

Collocations

strong
monoamine oxidasemonoamine neurotransmittermonoamine levelmonoamine hypothesismonoamine reuptake
medium
brain monoaminerelease monoaminesmonoamine metabolismclass of monoaminesessential monoamine
weak
certain monoaminesaffect monoamineinvolve monoaminestudy of monoamines

Examples

Examples of “monoamine” in a Sentence

verb

British English

  • Monoamine is not used as a verb.

American English

  • Monoamine is not used as a verb.

adverb

British English

  • Monoamine is not used as an adverb.

American English

  • Monoamine is not used as an adverb.

adjective

British English

  • The monoamine hypothesis of depression is a foundational theory.
  • They studied monoamine metabolism in the rodent model.

American English

  • Monoamine oxidase inhibitors are a class of antidepressants.
  • The research focused on monoamine neurotransmission pathways.

Usage

Meaning in Context

Business

Virtually unused, except potentially in highly specialised biotech/pharma company reports.

Academic

Core term in neuroscience, biochemistry, pharmacology, and psychology research papers and textbooks.

Everyday

Rare. Might appear in popular science articles or discussions about depression and medication.

Technical

High-frequency, precise term. Central to discussions of neurotransmission, psychopharmacology (MAOIs, SSRIs), and neuropsychiatric disorders.

Vocabulary

Synonyms of “monoamine”

Neutral

amine neurotransmitterbiogenic amine

Weak

Watch out

Common Mistakes When Using “monoamine”

  • Misspelling as 'monoamin' (dropping the 'e').
  • Incorrect plural: 'monoamines' is standard.
  • Mispronouncing as /ˌmɒnəʊˈeɪmaɪn/ (like 'amine' in 'vitamin'). The stress pattern is /...əʊəˈmiːn/.

FAQ

Frequently Asked Questions

It's a type of chemical in your brain that acts as a messenger between nerve cells, important for mood, movement, and motivation. Examples include serotonin and dopamine.

It's an enzyme that breaks down (metabolises) monoamine neurotransmitters. Inhibiting this enzyme (with MAOI drugs) increases the availability of these neurotransmitters.

No, it's a specialised scientific term. You will encounter it mainly in medical, psychological, or biochemical contexts, not in everyday conversation.

The three major monoamine neurotransmitters are serotonin, dopamine, and norepinephrine (noradrenaline).

Monoamine is usually technical/scientific (biochemistry, neurology, pharmacology, psychiatry) in register.

Monoamine: in British English it is pronounced /ˌmɒnəʊəˈmiːn/, and in American English it is pronounced /ˌmɑːnoʊəˈmiːn/. Tap the audio buttons above to hear it.

Learning

Memory Aids

Mnemonic

Think: MONO (one) + AMINE (a type of nitrogen compound). It's a SINGLE amine group on a molecule, crucial for mood.

Conceptual Metaphor

KEY MESSENGERS: Monoamines are often conceptualised as chemical messengers or signals in the brain's communication network.

Practice

Quiz

Fill in the gap
Old antidepressant drugs known as MAOIs work by inhibiting the enzyme oxidase.
Multiple Choice

Which of the following is NOT typically classified as a monoamine neurotransmitter?