monoamine oxidase: meaning, definition, pronunciation and examples

low
UK/ˌmɒnəʊeɪˌmiːn ˈɒksɪdeɪz/US/ˌmɑːnoʊəˌmiːn ˈɑːksɪdeɪz/

technical / scientific

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Quick answer

What does “monoamine oxidase” mean?

An enzyme that breaks down monoamine neurotransmitters in the brain and nervous system.

Audio

Pronunciation

Definition

Meaning and Definition

An enzyme that breaks down monoamine neurotransmitters in the brain and nervous system.

The enzyme system crucial for regulating neurotransmitters like serotonin, dopamine, and norepinephrine, with two main types (MAO-A and MAO-B) that are targets for certain antidepressant and neuroprotective drugs (MAO inhibitors).

Dialectal Variation

British vs American Usage

Differences

No significant lexical or spelling differences. Pronunciations may vary slightly (see IPA).

Connotations

None; strictly a scientific term.

Frequency

Equally low frequency in technical/scientific registers in both varieties.

Grammar

How to Use “monoamine oxidase” in a Sentence

inhibition of monoamine oxidaseMAO (monoamine oxidase)

Vocabulary

Collocations

strong
MAO inhibitormonoamine oxidase inhibitormonoamine oxidase activitymonoamine oxidase type A
medium
inhibit monoamine oxidaselevels of monoamine oxidaseblock monoamine oxidasemonoamine oxidase enzyme
weak
brain monoamine oxidasegenetic monoamine oxidaserelated to monoamine oxidase

Examples

Examples of “monoamine oxidase” in a Sentence

adjective

British English

  • The monoamine oxidase activity was measured.
  • She is on a monoamine oxidase inhibitor diet.

American English

  • The monoamine oxidase activity was measured.
  • He is taking a monoamine oxidase inhibitor medication.

Usage

Meaning in Context

Business

Extremely rare, except possibly in pharmaceutical company reports or biotech investment discussions.

Academic

Common in neuroscience, pharmacology, biochemistry, and psychiatry research papers and textbooks.

Everyday

Virtually never used in casual conversation.

Technical

The primary context. Used precisely in medical, pharmaceutical, and biochemical documentation, diagnostics, and treatment guidelines.

Vocabulary

Synonyms of “monoamine oxidase”

Neutral

MAO

Weak

amine oxidase

Watch out

Common Mistakes When Using “monoamine oxidase”

  • Pronouncing 'oxidase' with stress on the first syllable (OX-id-ase) instead of the standard /ˈɒksɪdeɪz/.
  • Using 'monoamine-oxidase' with an unnecessary hyphen.
  • Treating it as a plural noun (e.g., 'monoamine oxidases are...' is correct only when referring to types).

FAQ

Frequently Asked Questions

It is an enzyme that breaks down monoamine neurotransmitters like serotonin and dopamine, thereby regulating their levels in the brain.

A type of drug that blocks the action of monoamine oxidase, leading to increased levels of certain neurotransmitters. Used to treat depression and some neurological disorders.

Almost never. It is a specialised term used by healthcare professionals, neuroscientists, and pharmacologists.

Yes, the two main types are MAO-A and MAO-B, which break down different neurotransmitters and are targeted by different medications.

An enzyme that breaks down monoamine neurotransmitters in the brain and nervous system.

Monoamine oxidase is usually technical / scientific in register.

Monoamine oxidase: in British English it is pronounced /ˌmɒnəʊeɪˌmiːn ˈɒksɪdeɪz/, and in American English it is pronounced /ˌmɑːnoʊəˌmiːn ˈɑːksɪdeɪz/. Tap the audio buttons above to hear it.

Learning

Memory Aids

Mnemonic

MONOamine Oxidase: Remember it's ONE (mono) type of AMINE that this OXIDASE enzyme works on.

Conceptual Metaphor

A REGULATOR or CLEAN-UP CREW for brain chemicals; an enzyme that 'recycles' or 'deactivates' neurotransmitters.

Practice

Quiz

Fill in the gap
Certain antidepressants work by inhibiting the enzyme known as .
Multiple Choice

Monoamine oxidase is primarily relevant to which field?

Practise

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