monochloroacetic acid: meaning, definition, pronunciation and examples

C2 (Very low frequency; specialized technical term)
UK/ˌmɒnə(ʊ)ˌklɔːrəʊəˈsiːtɪk ˈæsɪd/US/ˌmɑːnoʊˌklɔːroʊəˈsiːtɪk ˈæsɪd/

Technical/scientific

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Quick answer

What does “monochloroacetic acid” mean?

A chlorinated derivative of acetic acid where one hydrogen atom is replaced by chlorine.

Audio

Pronunciation

Definition

Meaning and Definition

A chlorinated derivative of acetic acid where one hydrogen atom is replaced by chlorine.

A corrosive organic acid used as an intermediate in chemical synthesis, herbicide production, and biochemical research (e.g., in protein precipitation).

Dialectal Variation

British vs American Usage

Differences

No significant lexical differences. Potential minor spelling preference for 'sulph-' in related compounds in British English, but 'chloro-' is consistent.

Connotations

Exclusively technical with strong connotations of laboratory use, chemical hazard, and industrial processes.

Frequency

Extremely rare outside chemistry, biochemistry, and related industrial contexts. Frequency is identical in both varieties.

Grammar

How to Use “monochloroacetic acid” in a Sentence

[substance] is alkylated with monochloroacetic acid[agent] reacts with monochloroacetic acid to form [product]The preparation of [compound] involves monochloroacetic acid.

Vocabulary

Collocations

strong
synthesis of monochloroacetic acidaqueous monochloroacetic acidcrystalline monochloroacetic acidpurify monochloroacetic acid
medium
reaction with monochloroacetic acidsolution of monochloroacetic acidderivatives of monochloroacetic acid
weak
handle monochloroacetic acidcommercial monochloroacetic acidgrade monochloroacetic acid

Examples

Examples of “monochloroacetic acid” in a Sentence

adjective

British English

  • The monochloroacetic acid solution required careful handling.

American English

  • The monochloroacetic acid reagent was stored in a vented cabinet.

Usage

Meaning in Context

Business

Might appear in chemical supply catalogues or industrial production reports.

Academic

Common in organic chemistry, biochemistry, and chemical engineering literature.

Everyday

Virtually never used.

Technical

The primary domain of use: laboratory protocols, chemical patents, safety data sheets, and industrial process descriptions.

Vocabulary

Synonyms of “monochloroacetic acid”

Neutral

MCAchloroacetic acid (in context; though technically chloroacetic acid can refer to mono-, di-, or tri-)

Weak

ClCH₂COOH2-chloroacetic acid (systematic name)

Vocabulary

Antonyms of “monochloroacetic acid”

acetic acidunsubstituted acetic acid

Watch out

Common Mistakes When Using “monochloroacetic acid”

  • Misspelling as 'monochloracetic acid' (dropping the 'o').
  • Confusing it with 'dichloroacetic acid' or 'trichloroacetic acid', which have different properties.
  • Using it without appropriate hazard context (it is corrosive and toxic).

FAQ

Frequently Asked Questions

Yes, it is corrosive to skin, eyes, and respiratory tract, and requires proper safety equipment and handling procedures.

Its main uses are as an intermediate in the production of herbicides (e.g., 2,4-D), carboxymethyl cellulose (CMC), and other chemicals, and as a reagent in biochemical laboratories.

The chlorine atom makes it much more reactive and acidic than acetic acid, and also introduces significant toxicity and corrosivity.

In precise chemical communication, no, as 'chloroacetic acid' can be ambiguous. In specific industrial contexts where only the mono-substituted compound is discussed, it might be shortened informally.

A chlorinated derivative of acetic acid where one hydrogen atom is replaced by chlorine.

Monochloroacetic acid is usually technical/scientific in register.

Monochloroacetic acid: in British English it is pronounced /ˌmɒnə(ʊ)ˌklɔːrəʊəˈsiːtɪk ˈæsɪd/, and in American English it is pronounced /ˌmɑːnoʊˌklɔːroʊəˈsiːtɪk ˈæsɪd/. Tap the audio buttons above to hear it.

Learning

Memory Aids

Mnemonic

Think: MONO (one) CHLORO (chlorine atom) ACETIC ACID. It's acetic acid with one chlorine swap.

Conceptual Metaphor

A tool/modifier: often conceptualized as an 'alkylating agent' or a 'building block' in synthetic pathways.

Practice

Quiz

Fill in the gap
The carboxyl group in is highly reactive due to the electron-withdrawing effect of the chlorine atom.
Multiple Choice

Monochloroacetic acid is primarily classified as:

Practise

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