monoclonality: meaning, definition, pronunciation and examples
Very LowTechnical/Scientific
Quick answer
What does “monoclonality” mean?
The state or condition of being monoclonal.
Audio
Pronunciation
Definition
Meaning and Definition
The state or condition of being monoclonal; the property of cells or antibodies derived from a single clone or parent cell.
In immunology and oncology, the characteristic of a cell population originating from a single progenitor cell, often used to describe tumors or antibody production where all cells are genetically identical.
Dialectal Variation
British vs American Usage
Differences
No significant differences in meaning or usage. Spelling follows standard conventions (e.g., 'analyse' vs. 'analyze' in related contexts).
Connotations
Identical technical connotations in both varieties.
Frequency
Equally rare in both UK and US English, confined to specialist literature.
Grammar
How to Use “monoclonality” in a Sentence
The monoclonality of [noun phrase] was confirmed.Tests revealed monoclonality in the sample.Vocabulary
Collocations
Examples
Examples of “monoclonality” in a Sentence
adjective
British English
- The monoclonality analysis was conclusive.
- We require monoclonality data for the audit.
American English
- The monoclonality testing was completed.
- Monoclonality results are pending.
Usage
Meaning in Context
Business
Not used.
Academic
Used in research papers, theses, and textbooks in immunology, cancer biology, and molecular medicine.
Everyday
Virtually never used.
Technical
Core term in laboratory reports, diagnostic summaries, and clinical discussions regarding cancer or immune disorders.
Vocabulary
Synonyms of “monoclonality”
Strong
Neutral
Weak
Vocabulary
Antonyms of “monoclonality”
Watch out
Common Mistakes When Using “monoclonality”
- Misspelling as 'monoclonility' or 'monoclonality'.
- Using it as a countable noun (e.g., 'a monoclonality').
FAQ
Frequently Asked Questions
No, it is a highly specialised term used almost exclusively in medical and biological sciences.
'Monoclonality' explicitly means deriving from a single clone. 'Clonality' is a broader term that can refer to the property of being clonal, which may be mono- or polyclonal.
No, the adjective form is 'monoclonal'. 'Monoclonality' is a noun describing the state or property.
It can be crucial for cancer diagnosis, as many malignant tumours are monoclonal, indicating they grew from a single cancerous cell.
The state or condition of being monoclonal.
Monoclonality is usually technical/scientific in register.
Monoclonality: in British English it is pronounced /ˌmɒnə(ʊ)kləʊˈnalɪti/, and in American English it is pronounced /ˌmɑːnəkloʊˈnælɪti/. Tap the audio buttons above to hear it.
Phrases
Idioms & Phrases
- “None”
Learning
Memory Aids
Mnemonic
MONO (one) + CLONAL (from a single clone) + ITY (state of being) = the state of being from one clone.
Conceptual Metaphor
A FAMILY TREE with a single ancestor (all cells are descendants of one original cell).
Practice
Quiz
In which field is the term 'monoclonality' most commonly used?