retinoblastoma: meaning, definition, pronunciation and examples

very low
UK/ˌrɛtɪnəʊblæsˈtəʊmə/US/ˌrɛt̬ənoʊblæsˈtoʊmə/

technical/medical

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Quick answer

What does “retinoblastoma” mean?

A malignant tumour of the retina, occurring in young children.

Audio

Pronunciation

Definition

Meaning and Definition

A malignant tumour of the retina, occurring in young children.

A rare, cancerous tumour that develops in the light-sensitive lining at the back of the eye (retina). It is primarily an early childhood cancer and can be hereditary or sporadic.

Dialectal Variation

British vs American Usage

Differences

No significant differences in usage or definition. Spelling is identical.

Connotations

Identical connotations of a serious paediatric eye cancer.

Frequency

Extremely low frequency in both varieties, confined to medical contexts.

Grammar

How to Use “retinoblastoma” in a Sentence

patient with retinoblastomadiagnosis of retinoblastomatreatment for retinoblastomagene for retinoblastoma

Vocabulary

Collocations

strong
hereditary retinoblastomabilateral retinoblastomaretinoblastoma genetreat retinoblastomadiagnosis of retinoblastoma
medium
familial retinoblastomaunilateral retinoblastomaretinoblastoma tumourretinoblastoma protein
weak
rare retinoblastomaadvanced retinoblastomaretinoblastoma patientsurvival from retinoblastoma

Examples

Examples of “retinoblastoma” in a Sentence

adjective

British English

  • The retinoblastoma screening programme is for high-risk families.
  • They discussed retinoblastoma genetics.

American English

  • The retinoblastoma screening program is for high-risk families.
  • They discussed retinoblastoma genetics.

Usage

Meaning in Context

Business

Not used.

Academic

Used in medical and genetics research papers, e.g., 'The RB1 gene mutation is central to retinoblastoma pathogenesis.'

Everyday

Virtually never used in everyday conversation. A parent might say, 'My child was diagnosed with eye cancer.'

Technical

The standard term in ophthalmology, paediatric oncology, and genetics.

Vocabulary

Synonyms of “retinoblastoma”

Neutral

RB

Weak

retinal tumoureye cancer

Vocabulary

Antonyms of “retinoblastoma”

healthy retina

Watch out

Common Mistakes When Using “retinoblastoma”

  • Misspelling as 'retinablastoma' (missing 'o'), 'retinoblastomia', or 'retinoblast'].

FAQ

Frequently Asked Questions

Yes, when detected early, retinoblastoma has a very high cure rate (over 95% in developed countries), often with vision preservation.

It can be. Approximately 40% of cases are hereditary, caused by a germline mutation in the RB1 gene, and are often bilateral. The remaining 60% are sporadic and unilateral.

It is most often diagnosed before the age of 5, with the majority of cases presenting in the first two years of life.

Leukocoria, a white pupillary reflex often seen in photographs ('cat's eye reflex'), is the most common presenting sign.

A malignant tumour of the retina, occurring in young children.

Retinoblastoma is usually technical/medical in register.

Retinoblastoma: in British English it is pronounced /ˌrɛtɪnəʊblæsˈtəʊmə/, and in American English it is pronounced /ˌrɛt̬ənoʊblæsˈtoʊmə/. Tap the audio buttons above to hear it.

Learning

Memory Aids

Mnemonic

Think: 'RETINA' + 'BLAST' (as in blastoma, a tumour of embryonic tissue) + 'OMA' (tumour). A tumour blasting the retina.

Conceptual Metaphor

N/A. The term is a purely technical, non-metaphorical compound.

Practice

Quiz

Fill in the gap
A mutation in the RB1 gene is strongly associated with the development of .
Multiple Choice

Retinoblastoma is most accurately described as: