ribosome: meaning, definition, pronunciation and examples

C2/Technical
UK/ˈraɪ.bə.səʊm/US/ˈraɪ.bə.soʊm/

Technical/Scientific

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Quick answer

What does “ribosome” mean?

A tiny cellular structure where proteins are synthesised according to genetic instructions.

Audio

Pronunciation

Definition

Meaning and Definition

A tiny cellular structure where proteins are synthesised according to genetic instructions.

A complex molecular machine composed of ribosomal RNA and proteins, found in all living cells, that reads messenger RNA sequences and assembles amino acids into polypeptide chains.

Dialectal Variation

British vs American Usage

Differences

No difference in meaning. Spelling and pronunciation are identical. UK English may favour '-ise' ending but 'ribosome' is universally standardised.

Connotations

None beyond its scientific definition.

Frequency

Extremely rare in everyday conversation in both regions. Frequency is identical within the academic/technical register.

Grammar

How to Use “ribosome” in a Sentence

The ribosome translates/synthesises/produces [protein].[mRNA] is bound/decoded/read by the ribosome.The antibiotic inhibits/binds to/disrupts the ribosome.

Vocabulary

Collocations

strong
bound ribosomefree ribosomemitochondrial ribosomebacterial ribosomeeukaryotic ribosomeribosome biogenesis
medium
assemble on the ribosometarget the ribosomeribosome structureribosome profiling
weak
active ribosomelarge ribosomesmall ribosomecellular ribosome

Examples

Examples of “ribosome” in a Sentence

verb

British English

  • (Not applicable; no verb form.)

American English

  • (Not applicable; no verb form.)

adverb

British English

  • (Not applicable; no adverb form.)

American English

  • (Not applicable; no adverb form.)

adjective

British English

  • The ribosomal RNA (rRNA) is a key component.
  • They studied the ribosomal subunits.

American English

  • The antibiotic has a ribosomal target.
  • Ribosomal proteins are highly conserved.

Usage

Meaning in Context

Business

Not used, except in biotech/pharma company reports discussing drug mechanisms.

Academic

Core term in cell biology, molecular biology, biochemistry, and genetics.

Everyday

Virtually never used outside of advanced science education or documentaries.

Technical

The primary and only appropriate register. Used with precision to describe structure, function, and inhibition.

Vocabulary

Synonyms of “ribosome”

Neutral

protein factory (informal metaphor)translational machinery

Weak

organelle (ribosomes are not technically membrane-bound organelles)particle

Watch out

Common Mistakes When Using “ribosome”

  • Mispronunciation: /ˈrɪb.ə.soʊm/ (with a short 'i').
  • Misspelling: 'ribozome' (confusion with ribozyme, a catalytic RNA).
  • Confusing it with other organelles like the endoplasmic reticulum, which ribosomes can be attached to.

FAQ

Frequently Asked Questions

Traditionally, no. Ribosomes are not membrane-bound, which is a key feature of organelles. They are often classified as non-membranous cellular structures or macromolecular complexes.

No. Ribosomes are universal to all life forms—found in animal, plant, fungal, bacterial, and archaeal cells, highlighting their fundamental role in biology.

Free ribosomes float in the cytoplasm and make proteins for use within the cell. Bound ribosomes are attached to the endoplasmic reticulum and typically make proteins for export or for insertion into membranes.

Bacterial ribosomes have structural differences from human ribosomes. Antibiotics like streptomycin and erythromycin can bind to and disrupt bacterial ribosomes, halting their protein synthesis and killing the bacteria, without affecting human cells.

A tiny cellular structure where proteins are synthesised according to genetic instructions.

Ribosome is usually technical/scientific in register.

Ribosome: in British English it is pronounced /ˈraɪ.bə.səʊm/, and in American English it is pronounced /ˈraɪ.bə.soʊm/. Tap the audio buttons above to hear it.

Learning

Memory Aids

Mnemonic

Think: 'RIB-O-SOME'. Your RIBS protect vital organs. A ribo-SOME protects/supports the vital process of making proteins (some proteins).

Conceptual Metaphor

A PROTEIN SYNTHESIS FACTORY (reads a blueprint (mRNA) and assembles parts (amino acids) into a product (protein)).

Practice

Quiz

Fill in the gap
The genetic code in mRNA is deciphered and turned into a protein by the .
Multiple Choice

What is the primary function of a ribosome?