rna polymerase: meaning, definition, pronunciation and examples

C2
UK/ɑːr ɛn eɪ pɒˈlɪməreɪz/US/ɑːr ɛn eɪ pəˈlɪməˌreɪs/

Technical/Scientific

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Quick answer

What does “rna polymerase” mean?

The enzyme responsible for synthesizing RNA from a DNA template during transcription.

Audio

Pronunciation

Definition

Meaning and Definition

The enzyme responsible for synthesizing RNA from a DNA template during transcription.

In molecular biology, any of several complex enzymes that read the genetic code in DNA and produce a complementary RNA strand, a fundamental process in gene expression.

Dialectal Variation

British vs American Usage

Differences

No significant differences in meaning or usage. Spelling remains identical. Pronunciation may show minor stress variation.

Connotations

Purely scientific, no cultural connotations.

Frequency

Equally rare and technical in both varieties, used only in specialist contexts.

Grammar

How to Use “rna polymerase” in a Sentence

RNA polymerase [verb] the DNA templateThe [adj] RNA polymerase synthesizes RNARNA polymerase [number] is responsible for...

Vocabulary

Collocations

strong
bacterialeukaryoticDNA-dependentbacteriophagetranscription
medium
enzyme activitycore enzymeholoenzymecatalytic subunitinitiation complex
weak
majorspecificisolatedrecombinantpurified

Examples

Examples of “rna polymerase” in a Sentence

verb

British English

  • The RNA polymerase transcribes the gene.
  • The enzyme polymerises the ribonucleotides.

American English

  • RNA polymerase transcribes the DNA.
  • The polymerase initiates transcription.

adverb

British English

  • The gene was polymerase-dependently transcribed.

American English

  • The RNA was synthesized polymerase-independently.

adjective

British English

  • The RNA polymerase activity was assayed.
  • A polymerase-deficient mutant was isolated.

American English

  • The RNA polymerase complex is large.
  • Polymerase function is essential.

Usage

Meaning in Context

Academic

Heavy usage in life sciences research papers and textbooks. E.g., 'The study focused on the inhibition of RNA polymerase II in cancer cells.'

Everyday

Virtually never used.

Technical

Primary context. Central to laboratory protocols, genetic engineering, pharmaceutical development (e.g., antibiotics like rifampicin).

Vocabulary

Synonyms of “rna polymerase”

Strong

DNA-dependent RNA polymerase

Weak

transcription enzyme

Vocabulary

Antonyms of “rna polymerase”

Watch out

Common Mistakes When Using “rna polymerase”

  • Using lowercase 'rna' instead of 'RNA' (an acronym).
  • Misspelling 'polymerase' as 'polymersase' or 'polimerase'.
  • Confusing it with 'DNA polymerase'.
  • Using it without the necessary scientific context, making sentences incomprehensible to general audiences.

FAQ

Frequently Asked Questions

No, they are different enzymes. RNA polymerase synthesizes RNA using DNA as a template (transcription), while DNA polymerase synthesizes DNA using DNA as a template (replication).

It is essential for life as it performs transcription, the first step in gene expression, converting genetic information stored in DNA into RNA molecules that can be used to make proteins or perform other functions.

Yes. In eukaryotes, RNA Polymerase I, II, and III transcribe different classes of genes (rRNA, mRNA/tRNA, and tRNA/5S rRNA etc.). Bacteria typically have a single primary RNA polymerase.

No. It is a strictly technical, scientific term confined to molecular biology, genetics, medicine, and biotechnology. It has no everyday usage.

The enzyme responsible for synthesizing RNA from a DNA template during transcription.

Rna polymerase is usually technical/scientific in register.

Rna polymerase: in British English it is pronounced /ɑːr ɛn eɪ pɒˈlɪməreɪz/, and in American English it is pronounced /ɑːr ɛn eɪ pəˈlɪməˌreɪs/. Tap the audio buttons above to hear it.

Phrases

Idioms & Phrases

  • The workhorse of transcription

Learning

Memory Aids

Mnemonic

Think: RNA Poly-mer-ase: 'Poly' (makes many) 'mer' (units) of RNA, 'ase' (it's an enzyme). It's the factory assembly line that reads DNA blueprints and manufactures RNA products.

Conceptual Metaphor

A molecular scribe or copier; a factory assembly line reading a master template (DNA) to produce a product (RNA).

Practice

Quiz

Fill in the gap
The antibiotic rifampicin acts by directly inhibiting bacterial .
Multiple Choice

What is the primary function of RNA polymerase?