spermine: meaning, definition, pronunciation and examples

Low/Very Technical
UK/ˈspɜː.miːn/US/ˈspɝː.miːn/

Scientific, Medical, Biochemical

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Quick answer

What does “spermine” mean?

A crystalline organic compound (a polyamine) originally isolated from semen, now known to be present in all eukaryotic cells and involved in cellular metabolism.

Audio

Pronunciation

Definition

Meaning and Definition

A crystalline organic compound (a polyamine) originally isolated from semen, now known to be present in all eukaryotic cells and involved in cellular metabolism.

A specific polyamine, C₁₀H₂₆N₄, crucial for cell growth, proliferation, and stabilization of nucleic acids; a biomarker in certain medical and biochemical contexts.

Dialectal Variation

British vs American Usage

Differences

No significant lexical differences. Pronunciations differ slightly. Spelling is identical.

Connotations

Purely technical in both regions. The historical link to semen is irrelevant in professional contexts.

Frequency

Equally rare outside specialized fields in both regions.

Grammar

How to Use “spermine” in a Sentence

The analysis detected elevated *spermine*.*Spermine* stabilises the DNA helix.The pathway synthesises *spermine* from spermidine.

Vocabulary

Collocations

strong
spermine synthesisspermine levelsspermine oxidasespermine concentration
medium
intracellular sperminebiosynthesis of sperminespermine and spermidine
weak
spermine contentspermine bindingrole of spermine

Examples

Examples of “spermine” in a Sentence

noun

British English

  • The team measured the spermine in the tissue samples.
  • Spermine is vital for maintaining cell viability.

American English

  • The lab analyzed spermine levels in the tumor.
  • Spermine plays a key role in nucleic acid conformation.

adjective

British English

  • The spermine concentration was recorded.
  • They studied the spermine biosynthesis pathway.

American English

  • A spermine assay was performed.
  • The spermine-deficient mutant grew poorly.

Usage

Meaning in Context

Business

Virtually never used.

Academic

Used in biochemistry, cell biology, and medical research papers.

Everyday

Never used.

Technical

Core term in descriptions of polyamine metabolism, cancer research, and molecular biology protocols.

Vocabulary

Synonyms of “spermine”

Neutral

polyamine (broad category)

Vocabulary

Antonyms of “spermine”

spermine oxidase inhibitor (functional antagonist)spermine deficiency

Watch out

Common Mistakes When Using “spermine”

  • Confusing 'spermine' with 'sperm' or using it in a non-technical context.
  • Misspelling as 'spermin' or 'spermeen'.
  • Using it as a countable noun (e.g., 'a spermine') instead of an uncountable substance.

FAQ

Frequently Asked Questions

No. It was first isolated from semen, but it is a ubiquitous polyamine present in virtually all eukaryotic cells, essential for normal cellular function.

They are both polyamines. Spermidine is a precursor in the biosynthetic pathway that produces spermine. Spermine has a slightly longer molecular structure.

No. It is not a hormone secreted by glands to regulate distant tissues. It is a polyamine involved in intracellular processes like stabilizing DNA and RNA.

While some foods contain polyamines, dietary spermine is not a common concept. The body tightly regulates its polyamine levels through synthesis and breakdown.

A crystalline organic compound (a polyamine) originally isolated from semen, now known to be present in all eukaryotic cells and involved in cellular metabolism.

Spermine is usually scientific, medical, biochemical in register.

Spermine: in British English it is pronounced /ˈspɜː.miːn/, and in American English it is pronounced /ˈspɝː.miːn/. Tap the audio buttons above to hear it.

Learning

Memory Aids

Mnemonic

SPERMINE: A crucial compound found in all Cells, Originally from Semen, but Now Everywhere.

Conceptual Metaphor

A CELLULAR SCAFFOLDING / A MOLECULAR CHAPERONE (stabilising structures).

Practice

Quiz

Fill in the gap
The pathway converts spermidine into the polyamine spermine.
Multiple Choice

In which context is the term 'spermine' most appropriately used?

Practise

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