uric acid

C1
UK/ˌjʊər.ɪk ˈæs.ɪd/US/ˌjʊr.ɪk ˈæs.ɪd/

Technical/Scientific

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Definition

Meaning

A crystalline, nitrogenous compound that is the final product of purine metabolism, found in urine and blood.

A chemical compound (C5H4N4O3) formed from the breakdown of nucleic acids and purines, excessive levels of which are associated with medical conditions like gout and kidney stones.

Linguistics

Semantic Notes

The term is almost exclusively used in scientific, medical, and health-related contexts. It is a compound noun that functions as a singular, non-count noun (e.g., 'uric acid is high').

Dialectal Variation

British vs American Usage

Differences

No significant lexical or spelling differences. Pronunciation of the initial vowel may vary slightly (see IPA).

Connotations

Identical technical connotations. The term is associated with the same medical conditions in both varieties.

Frequency

Equally low frequency in general language but equally standard in scientific/medical contexts in both regions.

Vocabulary

Collocations

strong
elevated uric aciduric acid levelsuric acid crystalsuric acid productionuric acid metabolism
medium
excess uric acidhigh uric aciduric acid in the blooduric acid testreduce uric acid
weak
uric acid problemuric acid issueuric acid relateduric acid conditionuric acid content

Grammar

Valency Patterns

be linked to + [medical condition]lead to + [medical condition]be caused by + [high/ elevated] uric acidbe tested for uric acidto have + [high/ low] uric acid

Vocabulary

Synonyms

Neutral

UA (abbreviation in medical charts)

Weak

urate (related salt form, not a perfect synonym)nitrogenous waste product

Usage

Context Usage

Business

Potentially in contexts of pharmaceuticals, health supplements, or insurance underwriting related to health conditions.

Academic

Central term in biochemistry, physiology, and medical research papers on gout, kidney disease, or metabolic disorders.

Everyday

Mostly in personal health discussions, especially if someone has gout or related dietary concerns.

Technical

Core term in clinical pathology, rheumatology, nephrology, and laboratory medicine reports.

Examples

By Part of Speech

adjective

British English

  • uric acid concentration
  • uric acid measurement

American English

  • uric acid level
  • uric acid test

Examples

By CEFR Level

B1
  • The doctor said his uric acid was too high.
  • Eating less red meat can help lower uric acid.
B2
  • A diet high in purines increases the production of uric acid in the body.
  • Gout is caused by the formation of uric acid crystals in the joints.
C1
  • The pathologist's report indicated markedly elevated serum uric acid levels, consistent with a diagnosis of gouty arthritis.
  • Allopurinol is a xanthine oxidase inhibitor that reduces the synthesis of uric acid, thereby preventing urate crystal deposition.

Learning

Memory Aids

Mnemonic

Think: 'URine + IC' = URIC, the acid found in urine that can cause gout.

Conceptual Metaphor

Often conceptualised as SHARP CRYSTALS (e.g., 'needle-like uric acid crystals') or as POLLUTION/WASTE in the bloodstream (e.g., 'buildup of uric acid').

Watch out

Common Pitfalls

Translation Traps (for Russian speakers)

  • Avoid calquing as 'мочевая кислота' in every context—it's technically correct but English uses the fixed term 'uric acid'.
  • Do not confuse with 'urea' (карбамид/мочевина), which is a different nitrogenous compound.

Common Mistakes

  • Incorrect: 'urine acid'. Correct: 'uric acid'.
  • Incorrect pluralisation: 'urics acids' or 'uric acids'. It is a non-count noun.
  • Incorrect article use: 'an uric acid'. The initial sound is a consonant /j/, so use 'a uric acid level'.

Practice

Quiz

Fill in the gap
Patients with gout are often advised to avoid foods that increase production.
Multiple Choice

Which condition is most directly associated with high levels of uric acid?

FAQ

Frequently Asked Questions

No, they are different chemical compounds. Uric acid (C5H4N4O3) comes from purine breakdown, while urea (CH4N2O) is the main nitrogenous waste from protein metabolism.

Yes, though it's less commonly discussed. Abnormally low uric acid can be caused by certain medications, liver disease, or rare genetic disorders affecting its production.

Organ meats (liver, kidneys), certain seafood (anchovies, sardines, mussels), red meat, and some alcoholic beverages (especially beer) are high in purines.

It is measured via a blood test, often called a serum uric acid test, or sometimes through a 24-hour urine collection test.