fractionate: meaning, definition, pronunciation and examples

C2
UK/ˈfrakʃ(ə)neɪt/US/ˈfrækʃəˌneɪt/

Technical/Scientific

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Quick answer

What does “fractionate” mean?

To separate a mixture into its component parts.

Audio

Pronunciation

Definition

Meaning and Definition

To separate a mixture into its component parts.

To divide or break up something into smaller units, especially in a systematic or analytical way.

Dialectal Variation

British vs American Usage

Differences

No significant differences in meaning or usage.

Connotations

Primarily a neutral, precise technical term in both varieties.

Frequency

Equally rare in non-technical contexts in both BrE and AmE.

Grammar

How to Use “fractionate” in a Sentence

[Subject] fractionates [Object] (e.g., The column fractionates the mixture).[Subject] is fractionated into [Constituent Parts] (e.g., The oil was fractionated into various hydrocarbons).

Vocabulary

Collocations

strong
to fractionate a mixtureto fractionate plasmato fractionate crude oil
medium
fractionate the samplefractionate the componentsdifficult to fractionate
weak
carefully fractionatesuccessfully fractionatefractionate further

Examples

Examples of “fractionate” in a Sentence

verb

British English

  • The laboratory will fractionate the serum to isolate the antibodies.
  • We need to fractionate the whisky to achieve the desired purity.

American English

  • The refinery fractionates crude oil into gasoline and other products.
  • Researchers fractionated the compound using high-performance liquid chromatography.

adverb

British English

  • [No standard adverb form]

American English

  • [No standard adverb form]

adjective

British English

  • [No common adjectival form in use; 'fractionated' is the past participle used adjectivally, e.g., 'fractionated sample']

American English

  • [No common adjectival form in use; 'fractionated' is the past participle used adjectivally, e.g., 'fractionated plasma']

Usage

Meaning in Context

Business

Rare. Could be used metaphorically in finance (e.g., 'fractionate a large asset portfolio').

Academic

Common in scientific papers (chemistry, physics, biochemistry) to describe separation processes.

Everyday

Extremely rare. Would sound highly technical or jargonistic.

Technical

Core usage domain. Standard term in chemical engineering, laboratory science, and refining industries.

Vocabulary

Synonyms of “fractionate”

Vocabulary

Antonyms of “fractionate”

Watch out

Common Mistakes When Using “fractionate”

  • Using 'fractionate' as a general synonym for 'break' or 'divide' in non-technical writing.
  • Incorrect: 'The team was fractionated by internal disputes.' Correct: 'The team was fragmented/split by internal disputes.'

FAQ

Frequently Asked Questions

No, it is a specialized technical term primarily used in scientific and industrial contexts. It is very rare in everyday language.

The related nouns are 'fractionation' (the process) and 'fractionator' (the apparatus that performs fractionation).

It is possible but highly metaphorical and stylistically marked (e.g., 'The new policy threatened to fractionate the community'). In such contexts, words like 'divide', 'split', or 'fragment' are far more common and natural.

'Distill' is a specific type of fractionation based on differences in boiling points. 'Fractionate' is a broader term for any separation process that yields fractions (parts), which can include distillation, chromatography, or centrifugation.

To separate a mixture into its component parts.

Fractionate is usually technical/scientific in register.

Fractionate: in British English it is pronounced /ˈfrakʃ(ə)neɪt/, and in American English it is pronounced /ˈfrækʃəˌneɪt/. Tap the audio buttons above to hear it.

Phrases

Idioms & Phrases

  • [No common idioms]

Learning

Memory Aids

Mnemonic

Think of FRACTION-ATE: to turn something into its constituent fractions or parts.

Conceptual Metaphor

WHOLE IS SEPARATED INTO PARTS; ANALYSIS IS SEPARATION.

Practice

Quiz

Fill in the gap
In the petroleum industry, they use tall towers to crude oil into its usable components.
Multiple Choice

In which context is the verb 'fractionate' most appropriately used?